Benadryl and Blood potassium abnormal - a phase IV clinical study of FDA data

Summary:

Blood potassium abnormal is reported as a side effect among people who take Benadryl (diphenhydramine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tylenol, and have Vasculitis.

The phase IV clinical study analyzes which people have Blood potassium abnormal when taking Benadryl. It is created by eHealthMe based on reports of 100,139 people who have side effects when taking Benadryl from the FDA, and is updated regularly.

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 104,954 Benadryl users. Check the latest studies of Benadryl.

What is Blood potassium abnormal?

Blood potassium abnormal is found to be associated with 444 drugs and 427 conditions by eHealthMe. Check the latest studies of Blood potassium abnormal.

On Jul, 12, 2026

100,139 people reported to have side effects when taking Benadryl.
Among them, 28 people (0.03%) have Blood potassium abnormal.

Could Benadryl cause Blood potassium abnormal?

Among these 28 people:

How long have people been on Benadryl when they have Blood potassium abnormal? *

What is the gender of people who have Blood potassium abnormal when taking Benadryl? *

female: 65.22 %
male: 34.78 %

What is the age of people who have Blood potassium abnormal when taking Benadryl? *

What are other drugs people take besides Benadryl? *

Tylenol: 9 people, 32.14%
Zofran: 6 people, 21.43%
Folic Acid: 6 people, 21.43%
Prednisone: 6 people, 21.43%
Acetaminophen: 5 people, 17.86%
Diovan: 5 people, 17.86%
Celebrex: 5 people, 17.86%
Decadron: 5 people, 17.86%
Diphenhydramine Hydrochloride: 4 people, 14.29%
Amlodipine Besylate: 4 people, 14.29%

What are other side effects people have besides Blood potassium abnormal? *

Nausea (feeling of having an urge to vomit): 10 people, 35.71%
Nausea And Vomiting: 9 people, 32.14%
Dizziness: 8 people, 28.57%
Neuralgia (pain in one or more nerves): 7 people, 25.00%
High Blood Pressure: 7 people, 25.00%
Weight Increased: 6 people, 21.43%
Pain: 6 people, 21.43%
Fatigue (feeling of tiredness): 6 people, 21.43%
Headache (pain in head): 6 people, 21.43%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 21.43%

What are the existing conditions these people have? *

Vasculitis (inflammation of a blood vessel or blood vessels): 6 people, 21.43%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 17.86%
Pain: 3 people, 10.71%
Nausea (feeling of having an urge to vomit): 2 people, 7.14%
High Blood Pressure: 2 people, 7.14%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 2 people, 7.14%
Pain In Extremity: 2 people, 7.14%
Mesothelioma (rare type of cancer that occurs in the thin layer of cells lining the body's internal organs, known as the mesothelium): 2 people, 7.14%
Headache (pain in head): 1 person, 3.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Benadryl and have Blood potassium abnormal?

- Check whether Blood potassium abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Benadryl:

Benadryl (104,954 reports)

Browse all side effects of Benadryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blood potassium abnormal:

Blood potassium abnormal (444 drugs)

Browse all the conditions that are associated with Blood potassium abnormal:

Blood potassium abnormal (427 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride (the active ingredients of Benadryl) and Benadryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.