Benadryl and Skin blushing/flushing - a phase IV clinical study of FDA data

Summary:

Skin blushing/flushing is found among people who take Benadryl, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Benadryl and have Skin blushing/flushing. It is created by eHealthMe based on reports of 85,073 people who have side effects when taking Benadryl from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 09, 2023

85,073 people reported to have side effects when taking Benadryl.
Among them, 2,801 people (3.29%) have Skin blushing/flushing.

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 89,808 Benadryl users for its effectiveness, alternative drugs and more.

What is Skin blushing/flushing?

Skin blushing/flushing (a sudden reddening of the face, neck) is found to be associated with 3,556 drugs and 2,857 conditions by eHealthMe.

Number of Benadryl and Skin blushing/flushing reports submitted per year:

Could Benadryl cause Skin blushing/flushing?

* Approximation only. Some reports may have incomplete information.

Do you take Benadryl and have Skin blushing/flushing?

Check whether Skin blushing/flushing is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Skin blushing/flushing and when was it recovered:

Skin blushing/flushing in Benadryl

Expand to all the drugs that have ingredients of diphenhydramine hydrochloride:

Skin blushing/flushing and drugs with ingredients of diphenhydramine hydrochloride (4,131 reports)

Alternative drugs to, pros and cons of Benadryl:

Benadryl (89,808 reports)

Common Benadryl side effects:

Fatigue (feeling of tiredness): 9,980 reports
Rashes (redness): 8,746 reports
Headache (pain in head): 7,794 reports
Breathing difficulty: 7,637 reports
Pain: 6,908 reports
Itching: 6,738 reports

Browse all side effects of Benadryl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Skin blushing/flushing treatments and more:

Skin blushing/flushing (107,578 reports)

COVID vaccines that are related to Skin blushing/flushing:

Common drugs associated with Skin blushing/flushing:

All the drugs that are associated with Skin blushing/flushing:

Skin blushing/flushing (3,556 drugs)

Common conditions associated with Skin blushing/flushing:

Multiple sclerosis: 20,241 reports
High blood cholesterol: 11,039 reports
Primary pulmonary hypertension: 5,307 reports
High blood pressure: 3,116 reports

All the conditions that are associated with Skin blushing/flushing:

Skin blushing/flushing (2,857 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride (the active ingredients of Benadryl) and Benadryl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.