Bextra and Emphysema - a phase IV clinical study of FDA data

Summary:

Emphysema is reported as a side effect among people who take Bextra (valdecoxib), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Emphysema when taking Bextra. It is created by eHealthMe based on reports of 20,982 people who have side effects when taking Bextra from the FDA, and is updated regularly.

What is Bextra?

Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.

What is Emphysema?

Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs) is found to be associated with 1,076 drugs and 1,096 conditions by eHealthMe. Check the latest studies of Emphysema.



On Jul, 16, 2026

20,982 people reported to have side effects when taking Bextra.
Among them, 79 people (0.38%) have Emphysema.

Could Bextra cause Emphysema?

Among these 79 people:

How long have people been on Bextra when they have Emphysema? *

  • < 1 month: 25 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 25 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Emphysema when taking Bextra? *

  • female: 77.92 %
  • male: 22.08 %

What is the age of people who have Emphysema when taking Bextra? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 1.67 %
  • 30-39: 0.0 %
  • 40-49: 1.67 %
  • 50-59: 48.33 %
  • 60+: 48.33 %

What are other drugs people take besides Bextra? *

  1. Zometa: 44 people, 55.70%
  2. Celebrex: 39 people, 49.37%
  3. Fosamax: 32 people, 40.51%
  4. Advair Diskus 100/50: 30 people, 37.97%
  5. Xanax: 28 people, 35.44%
  6. Lasix: 28 people, 35.44%
  7. Prilosec: 26 people, 32.91%
  8. Nasonex: 25 people, 31.65%
  9. Allegra: 24 people, 30.38%
  10. Lexapro: 24 people, 30.38%

What are other side effects people have besides Emphysema? *

  1. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 47 people, 59.49%
  2. Stress And Anxiety: 47 people, 59.49%
  3. Chest Pain: 41 people, 51.90%
  4. Injury: 41 people, 51.90%
  5. Osteonecrosis Of Jaw (death of bone of jaw): 40 people, 50.63%
  6. Back Pain: 34 people, 43.04%
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 34 people, 43.04%
  8. Atelectasis (partial or complete collapse of the lung): 34 people, 43.04%
  9. Enlarged Heart: 33 people, 41.77%
  10. Osteopenia (a condition where bone mineral density is lower than normal): 33 people, 41.77%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 22 people, 27.85%
  2. Bone Density Abnormal: 16 people, 20.25%
  3. Breast Cancer Metastatic: 11 people, 13.92%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 9 people, 11.39%
  5. High Blood Pressure: 8 people, 10.13%
  6. Osteoporosis (bones weak and more likely to break): 7 people, 8.86%
  7. Breast Cancer: 6 people, 7.59%
  8. Back Pain: 5 people, 6.33%
  9. High Blood Cholesterol: 5 people, 6.33%
  10. Hypersensitivity: 5 people, 6.33%

* Approximation only. Some reports may have incomplete information.

Do you take Bextra and have Emphysema?

- Check whether Emphysema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bextra:

Emphysema treatments and more:

How severe was Emphysema and when was it recovered:

Expand to all the drugs that have ingredients of valdecoxib:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bextra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Emphysema:

Browse all the conditions that are associated with Emphysema:


How the study uses the data?

The study uses data from the FDA. It is based on valdecoxib (the active ingredients of Bextra) and Bextra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: