Repatha and Valtrex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Repatha (evolocumab) and Valtrex (valacyclovir hydrochloride). Common drug interactions include alopecia among females and bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Repatha and Valtrex. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.

What is Valtrex?

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 39,999 Valtrex users. Check the latest studies of Valtrex.

On Jul, 16, 2026

48 people who take Repatha and Valtrex together, and have interactions are studied.

What are the common drug interactions of Repatha and Valtrex, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
Bone pain
Breast pain
Death
Decreased activity
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Distractibility (inability to sustain one's attention)
Drug intolerance (drug sensitivity)

male:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Infusion site haemorrhage (bleeding from infusion site)
Coronary arterial stent insertion
Tooth abscess (pus formation in tooth)
Presyncope
Viral infection
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Arthralgia (joint pain)
Arthropathy
Asthenia (weakness)

What are the common drug interactions of Repatha and Valtrex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Disturbance in attention
Drug ineffective
Feeling jittery
Initial insomnia (feeling of inadequate or poor-quality sleep)
Nightmare (unpleasant dream)
Paradoxical drug reaction
Sleep disorder

40-49:

n/a

50-59:

Speech disorder
Tremor (trembling or shaking movements in one or more parts of your body)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Dizziness
Back pain
Fatigue (feeling of tiredness)
Influenza like illness
Pain
Sleep disorder due to general medical condition, insomnia type (a conditions that prevent a person from getting restful sleep due to mental condition of not getting sleep)
Upper respiratory tract infection

60+:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Infusion site haemorrhage (bleeding from infusion site)
Hypertension (high blood pressure)
Blood glucose increased
Blood potassium decreased
Chest pain
Dizziness
Eye infection
Glycosylated haemoglobin increased
Infusion site extravasation (flow of (blood or lymph) from infusion site)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 7 people, 14.58%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 8.33%
Muscle Spasms (muscle contraction): 3 people, 6.25%
Multiple Myeloma (cancer of the plasma cells): 3 people, 6.25%
High Blood Pressure: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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