Nuvigil and Hydrocodone bitartrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nuvigil (armodafinil) and Hydrocodone bitartrate (hydrocodone bitartrate). Common drug interactions include abnormal sleep-related event among females and aortic aneurysm among males.

The phase IV clinical study analyzes what interactions people have when they take Nuvigil and Hydrocodone bitartrate. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Nuvigil?

Nuvigil has active ingredients of armodafinil. It is often used in narcolepsy. eHealthMe is studying from 23,669 Nuvigil users. Check the latest studies of Nuvigil.

What is Hydrocodone bitartrate?

Hydrocodone bitartrate has active ingredients of hydrocodone bitartrate. It is often used in chronic pain. eHealthMe is studying from 5,380 Hydrocodone bitartrate users. Check the latest studies of Hydrocodone bitartrate.

On Jul, 16, 2026

12 people who take Nuvigil and Hydrocodone bitartrate together, and have interactions are studied.

Nuvigil and Hydrocodone bitartrate drug interactions.

What are the common drug interactions of Nuvigil and Hydrocodone Bitartrate, by gender? *:

female:

Abnormal sleep-related event
Anxiety
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Basilar migraine (migraine with neurological symptoms related to the brain stem or with neurological symptoms on both sides of the body)
Blood cholesterol increased
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Cardiac murmur (an heart sound in valve abnormality)
Cardiomegaly (increased size of heart than normal)
Cataract (clouding of the lens inside the eye)
Chills (felling of cold)

male:

Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cardiomegaly (increased size of heart than normal)
Dyspnoea exertional (breathlessness or shortness of breath)
Intervertebral disc protrusion (spinal disc protrusion)
Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Nuvigil and Hydrocodone Bitartrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypertension (high blood pressure)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

40-49:

Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cardiomegaly (increased size of heart than normal)
Dyspnoea exertional (breathlessness or shortness of breath)
Intervertebral disc protrusion (spinal disc protrusion)
Pulmonary embolism (blockage of the main artery of the lung)
Basilar migraine (migraine with neurological symptoms related to the brain stem or with neurological symptoms on both sides of the body)
Chills (felling of cold)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Hepatic enzyme increased

50-59:

Cardiac murmur (an heart sound in valve abnormality)
Cataract (clouding of the lens inside the eye)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypertension (high blood pressure)
Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)
Oedema (fluid collection in tissue)
Osteoporosis (bones weak and more likely to break)
Anxiety
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)

60+:

Depression
Hypertension (high blood pressure)
Hysterectomy
Lichen sclerosus (a skin disorder that causes the skin to become thin, whitened, wrinkled, and can cause itching and pain)
Nausea (feeling of having an urge to vomit)
Pain
Road traffic accident
Suicidal ideation

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 58.33%
Weight Decreased: 1 person, 8.33%
High Blood Cholesterol: 1 person, 8.33%
Drowsiness: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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