Thorazine and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Thorazine (chlorpromazine hydrochloride) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include alanine aminotransferase increased among females and emotional disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Thorazine and Adderall. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Thorazine?

Thorazine has active ingredients of chlorpromazine hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 3,237 Thorazine users. Check the latest studies of Thorazine.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.



On Jul, 16, 2026

22 people who take Thorazine and Adderall together, and have interactions are studied.

Thorazine and Adderall drug interactions.

What are the common drug interactions of Thorazine and Adderall, by gender? *:

female:

  1. Alanine aminotransferase increased
  2. Dyspnoea (difficult or laboured respiration)
  3. Fatigue (feeling of tiredness)
  4. Heart rate increased
  5. Hunger
  6. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  7. Periodic limb movement disorder
  8. Sleep paralysis (waking up and unable to move or speak)
  9. Snoring
  10. Weight increased

male:

  1. Emotional disorder
  2. Weight increased
  3. Blood glucose increased
  4. Crying
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  7. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  8. Gynaecomastia (enlargement of the gland tissue of the male breast)
  9. Hypoglycaemia (deficiency of glucose in the bloodstream)
  10. Neuropathy peripheral (surface nerve damage)

What are the common drug interactions of Thorazine and Adderall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Hyperglycaemia (high blood sugar)
  2. Tardive dyskinesia (a disorder that involves involuntary movements)

10-19:

  1. Anger
  2. Crying
  3. Emotional disorder
  4. Gynaecomastia (enlargement of the gland tissue of the male breast)
  5. Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups)
  6. Weight increased

20-29:

  1. Drug ineffective

30-39:

  1. Back disorder
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Diabetes mellitus inadequate control
  4. Hyperglycaemia (high blood sugar)
  5. Hypotension (abnormally low blood pressure)
  6. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  7. Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
  8. Overdose
  9. Pancreatitis (inflammation of pancreas)
  10. Type 2 diabetes mellitus

40-49:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Diabetes mellitus inadequate control
  3. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  4. Type 2 diabetes mellitus

50-59:

  1. Alanine aminotransferase increased
  2. Fatigue (feeling of tiredness)
  3. Hunger
  4. Merycism (a rare disease in which food is chewed, swallowed, and then returned to the mouth and chewed again)
  5. Muscle spasms (muscle contraction)
  6. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  7. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  8. Periodic limb movement disorder
  9. Pseudodementia (severe form of depression that results from a progressive brain disorder in which cognitive changes mimic those of dementia)
  10. Sleep paralysis (waking up and unable to move or speak)

60+:

n/a

What are the existing conditions these people have? *

  1. Stress And Anxiety: 8 people, 36.36%
  2. Sleep Disorder: 5 people, 22.73%
  3. Pain: 4 people, 18.18%
  4. Insomnia (sleeplessness): 4 people, 18.18%
  5. Depression: 4 people, 18.18%
  6. High Blood Cholesterol: 3 people, 13.64%
  7. Agitation (state of anxiety or nervous excitement): 3 people, 13.64%
  8. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 2 people, 9.09%
  9. Nausea (feeling of having an urge to vomit): 2 people, 9.09%
  10. Migraine (headache): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Thorazine and Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Thorazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Thorazine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adderall and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on chlorpromazine hydrochloride and amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Thorazine and Adderall, respectively), and Thorazine and Adderall (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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