Bextra and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Bextra (valdecoxib), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Effexor, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Bextra. It is created by eHealthMe based on reports of 20,982 people who have side effects when taking Bextra from the FDA, and is updated regularly.

What is Bextra?

Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,041 drugs and 1,419 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.

On Dec, 23, 2025

20,982 people reported to have side effects when taking Bextra.
Among them, 28 people (0.13%) have Hyperthyroidism.

Among these 28 people:

How long have people been on Bextra when they have Hyperthyroidism? *

What is the gender of people who have Hyperthyroidism when taking Bextra? *

female: 96.43 %
male: 3.57 %

What is the age of people who have Hyperthyroidism when taking Bextra? *

What are other drugs people take besides Bextra? *

What are other side effects people have besides Hyperthyroidism? *

Stress And Anxiety: 11 people, 39.29%
Injury: 11 people, 39.29%
Nausea (feeling of having an urge to vomit): 11 people, 39.29%
Weight Decreased: 10 people, 35.71%
Nausea And Vomiting: 10 people, 35.71%
Fatigue (feeling of tiredness): 10 people, 35.71%
Tremor (trembling or shaking movements in one or more parts of your body): 9 people, 32.14%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 9 people, 32.14%
Headache (pain in head): 9 people, 32.14%
Cough: 9 people, 32.14%

What are the existing conditions these people have? *

Breast Cancer: 6 people, 21.43%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 21.43%
High Blood Pressure: 6 people, 21.43%
Depression: 5 people, 17.86%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 14.29%
Back Pain: 4 people, 14.29%
Migraine (headache): 4 people, 14.29%
Stress And Anxiety: 3 people, 10.71%
Bipolar Disorder (mood disorder): 2 people, 7.14%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Bextra and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition (FREE)
- Predict drug outcomes for up to one year with AI (FREE)
- Get an AI agent to monitor your drugs continuously (FREE)

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Bextra:

Bextra (20,994 reports)

Hyperthyroidism treatments and more:

Hyperthyroidism (26,827 reports)

Browse all side effects of Bextra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Hyperthyroidism (1,041 drugs)

Browse all the conditions that are associated with Hyperthyroidism:

Hyperthyroidism (1,419 conditions)

Drugs similar to Bextra and Hyperthyroidism :

Related publications that referenced our studies

Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .
Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on valdecoxib (the active ingredients of Bextra) and Bextra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.