Brintellix and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Brintellix (vortioxetine hydrobromide), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Nexium, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Brintellix. It is created by eHealthMe based on reports of 6,619 people who have side effects when taking Brintellix from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,837 drugs and 4,494 conditions by eHealthMe. Check the latest studies of Acute kidney failure.

On Jul, 10, 2026

6,619 people reported to have side effects when taking Brintellix.
Among them, 12 people (0.18%) have Acute kidney failure.

Could Brintellix cause Acute kidney failure?

Among these 12 people:

How long have people been on Brintellix when they have Acute kidney failure? *

What is the gender of people who have Acute kidney failure when taking Brintellix? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Acute kidney failure when taking Brintellix? *

What are other drugs people take besides Brintellix? *

What are other side effects people have besides Acute kidney failure? *

Chronic Kidney Disease: 8 people, 66.67%
Interstitial Nephritis (inflammation of the kidney): 4 people, 33.33%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 2 people, 16.67%
Renal Injury (kidney injury): 2 people, 16.67%
Nephrogenic Anaemia (anaemia due to kidney disease): 2 people, 16.67%
Indigestion: 2 people, 16.67%
Fatigue (feeling of tiredness): 1 person, 8.33%
Agitation (state of anxiety or nervous excitement): 1 person, 8.33%
Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 1 person, 8.33%
Celiac Disease - Sprue (a disease of the small intestine): 1 person, 8.33%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 75.00%
High Blood Pressure: 7 people, 58.33%
High Blood Cholesterol: 6 people, 50.00%
Pain: 4 people, 33.33%
Stress And Anxiety: 4 people, 33.33%
Hypersensitivity: 3 people, 25.00%
Infection: 3 people, 25.00%
Insomnia (sleeplessness): 3 people, 25.00%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 25.00%
Diabetes: 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Brintellix and have Acute kidney failure?

- Check whether Acute kidney failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Brintellix:

Brintellix (6,748 reports)

Browse all side effects of Brintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Acute kidney failure (2,837 drugs)

Browse all the conditions that are associated with Acute kidney failure:

Acute kidney failure (4,494 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on vortioxetine hydrobromide (the active ingredients of Brintellix) and Brintellix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.