Brintellix and Glaucoma - a phase IV clinical study of FDA data

Summary:

Glaucoma is reported as a side effect among people who take Brintellix (vortioxetine hydrobromide), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Folic Acid, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Glaucoma when taking Brintellix. It is created by eHealthMe based on reports of 6,619 people who have side effects when taking Brintellix from the FDA, and is updated regularly.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.

What is Glaucoma?

Glaucoma (increased fluid pressure in the eye with vision loss) is found to be associated with 1,236 drugs and 1,655 conditions by eHealthMe. Check the latest studies of Glaucoma.

On May, 13, 2026

6,619 people reported to have side effects when taking Brintellix.
Among them, 15 people (0.23%) have Glaucoma.

Among these 15 people:

How long have people been on Brintellix when they have Glaucoma? *

What is the gender of people who have Glaucoma when taking Brintellix? *

female: 69.23 %
male: 30.77 %

What is the age of people who have Glaucoma when taking Brintellix? *

What are other drugs people take besides Brintellix? *

What are other side effects people have besides Glaucoma? *

Headache (pain in head): 3 people, 20.00%
Dizziness: 2 people, 13.33%
Intraocular Pressure Increased: 2 people, 13.33%
Vision Blurred: 1 person, 6.67%
Trance: 1 person, 6.67%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 1 person, 6.67%
Brain Neoplasm (tumour of brain): 1 person, 6.67%
Eyelid Margin Crusting (crusting at the lid margins, generally worse on waking): 1 person, 6.67%
Fatigue (feeling of tiredness): 1 person, 6.67%
Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 1 person, 6.67%

What are the existing conditions these people have? *

Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 6 people, 40.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 40.00%
Stress And Anxiety: 4 people, 26.67%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 1 person, 6.67%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Brintellix and have Glaucoma?

- Check whether Glaucoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Brintellix:

Brintellix (6,748 reports)

Glaucoma treatments and more:

Glaucoma (61,926 reports)

Browse all side effects of Brintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Glaucoma:

Glaucoma (1,236 drugs)

Browse all the conditions that are associated with Glaucoma:

Glaucoma (1,655 conditions)

Related publications that referenced our studies

Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on vortioxetine hydrobromide (the active ingredients of Brintellix) and Brintellix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.