Buprenorphine and Hypersensitivity - a phase IV clinical study of FDA data

Summary:

Hypersensitivity is reported as a side effect among people who take Buprenorphine (buprenorphine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Suboxone, and have Pain.

The phase IV clinical study analyzes which people have Hypersensitivity when taking Buprenorphine. It is created by eHealthMe based on reports of 8,918 people who have side effects when taking Buprenorphine from the FDA, and is updated regularly.

What is Buprenorphine?

Buprenorphine has active ingredients of buprenorphine. It is often used in opioid intoxication. eHealthMe is studying from 9,053 Buprenorphine users. Check the latest studies of Buprenorphine.

What is Hypersensitivity?

Hypersensitivity is found to be associated with 2,751 drugs and 2,913 conditions by eHealthMe. Check the latest studies of Hypersensitivity.

On Jul, 16, 2026

8,918 people reported to have side effects when taking Buprenorphine.
Among them, 54 people (0.61%) have Hypersensitivity.

Could Buprenorphine cause Hypersensitivity?

Among these 54 people:

How long have people been on Buprenorphine when they have Hypersensitivity? *

What is the gender of people who have Hypersensitivity when taking Buprenorphine? *

female: 67.35 %
male: 32.65 %

What is the age of people who have Hypersensitivity when taking Buprenorphine? *

What are other drugs people take besides Buprenorphine? *

What are other side effects people have besides Hypersensitivity? *

Rashes (redness): 12 people, 22.22%
Malaise (a feeling of general discomfort or uneasiness): 8 people, 14.81%
Drug Ineffective: 8 people, 14.81%
Itching: 7 people, 12.96%
Dyspnea (difficult or laboured breathing): 7 people, 12.96%
Depression: 6 people, 11.11%
Pain: 5 people, 9.26%
Wheezing (a high-pitched whistling sound made while you breath): 5 people, 9.26%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 5 people, 9.26%
Nausea (feeling of having an urge to vomit): 4 people, 7.41%

What are the existing conditions these people have? *

Pain: 9 people, 16.67%
Depression: 5 people, 9.26%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 5.56%
Otitis Media (inflammation of the middle ear): 3 people, 5.56%
Insomnia (sleeplessness): 3 people, 5.56%
Constipation: 2 people, 3.70%
Lyme Disease (a bacterial infection that is spread to humans by infected ticks): 2 people, 3.70%
Drug Dependence: 2 people, 3.70%
Upper Limb Fracture: 1 person, 1.85%
Gastric Ulcer (stomach ulcer): 1 person, 1.85%

* Approximation only. Some reports may have incomplete information.

Do you take Buprenorphine and have Hypersensitivity?

- Check whether Hypersensitivity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Buprenorphine:

Buprenorphine (9,053 reports)

Hypersensitivity treatments and more:

Hypersensitivity (272,618 reports)

Browse all side effects of Buprenorphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypersensitivity:

Hypersensitivity (2,751 drugs)

Browse all the conditions that are associated with Hypersensitivity:

Hypersensitivity (2,913 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on buprenorphine (the active ingredients of Buprenorphine) and Buprenorphine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.