Cafergot and Bone density decreased - a phase IV clinical study of FDA data

Summary:

Bone density decreased is reported as a side effect among people who take Cafergot (caffeine; ergotamine tartrate), especially for people who are female, 60+ old, also take Fosamax, and have Oestrogen deficiency.

The phase IV clinical study analyzes which people have Bone density decreased when taking Cafergot. It is created by eHealthMe based on reports of 514 people who have side effects when taking Cafergot from the FDA, and is updated regularly.

What is Cafergot?

Cafergot has active ingredients of caffeine; ergotamine tartrate. It is often used in migraine. eHealthMe is studying from 531 Cafergot users. Check the latest studies of Cafergot.

What is Bone density decreased?

Bone density decreased is found to be associated with 1,122 drugs and 947 conditions by eHealthMe. Check the latest studies of Bone density decreased.

On Aug, 02, 2026

514 people reported to have side effects when taking Cafergot.
Among them, 12 people (2.33%) have Bone density decreased.

Could Cafergot cause Bone density decreased?

Among these 12 people:

What is the gender of people who have Bone density decreased when taking Cafergot? *

female: 100 %
male: 0.0 %

What is the age of people who have Bone density decreased when taking Cafergot? *

What are other drugs people take besides Cafergot? *

Fosamax: 11 people, 91.67%

What are other side effects people have besides Bone density decreased? *

Sensitivity Of Teeth: 12 people, 100.00%
Toothaches (tooth pain): 12 people, 100.00%
Anaemia (lack of blood): 11 people, 91.67%
Arthropathy: 10 people, 83.33%
Oral Infection: 10 people, 83.33%
Impaired Healing: 10 people, 83.33%
Pulpitis Dental (inflammation of the tooth pulp): 9 people, 75.00%
Hair Loss: 9 people, 75.00%
Dental Caries: 9 people, 75.00%
Dental Fistula: 9 people, 75.00%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 11 people, 91.67%
Osteopenia (a condition where bone mineral density is lower than normal): 11 people, 91.67%
Oestrogen Deficiency (lack of estrogens): 11 people, 91.67%

* Approximation only. Some reports may have incomplete information.

Do you take Cafergot and have Bone density decreased?

- Check whether Bone density decreased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cafergot:

Cafergot (531 reports)

Browse all side effects of Cafergot:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone density decreased:

Bone density decreased (1,122 drugs)

Browse all the conditions that are associated with Bone density decreased:

Bone density decreased (947 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on caffeine; ergotamine tartrate (the active ingredients of Cafergot) and Cafergot (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.