Ceftriaxone and Aggression - a phase IV clinical study of FDA data

Summary:

Aggression is reported as a side effect among people who take Ceftriaxone (ceftriaxone sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lorazepam, and have Pneumonia.

The phase IV clinical study analyzes which people have Aggression when taking Ceftriaxone. It is created by eHealthMe based on reports of 40,872 people who have side effects when taking Ceftriaxone from the FDA, and is updated regularly.

What is Ceftriaxone?

Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.

What is Aggression?

Aggression is found to be associated with 1,523 drugs and 1,965 conditions by eHealthMe. Check the latest studies of Aggression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

40,872 people reported to have side effects when taking Ceftriaxone.
Among them, 66 people (0.16%) have Aggression.

Among these 66 people:

How long have people been on Ceftriaxone when they have Aggression? *

What is the gender of people who have Aggression when taking Ceftriaxone? *

female: 27.42 %
male: 72.58 %

What is the age of people who have Aggression when taking Ceftriaxone? *

What are other drugs people take besides Ceftriaxone? *

What are other side effects people have besides Aggression? *

Agitation (state of anxiety or nervous excitement): 23 people, 34.85%
Fever: 19 people, 28.79%
Confusional State: 18 people, 27.27%
Confusion: 13 people, 19.70%
Acute Psychosis (period of mentally unstable behaviour): 9 people, 13.64%
Abnormal Behavior: 9 people, 13.64%
Weight Decreased: 8 people, 12.12%
Mucosal Inflammation (infection of mucous membrane): 8 people, 12.12%
Pain In Jaw: 7 people, 10.61%
Obstructive Airways Disorder (a progressive disease that makes it hard to breathe): 7 people, 10.61%

What are the existing conditions these people have? *

Pneumonia: 9 people, 13.64%
High Blood Pressure: 8 people, 12.12%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 10.61%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 5 people, 7.58%
Type 2 Diabetes: 5 people, 7.58%
Ankylosing Spondylitis (type of arthritis affecting the spine): 5 people, 7.58%
Pneumocystis Jiroveci Pneumonia (fungal infection of the lungs): 5 people, 7.58%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 6.06%
Pulmonary Tuberculosis (lungs tuberculosis): 3 people, 4.55%
Urinary Tract Infection: 3 people, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Ceftriaxone and have Aggression?

- Check whether Aggression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ceftriaxone:

Ceftriaxone (40,991 reports)

Aggression treatments and more:

Aggression (65,312 reports)

Browse all side effects of Ceftriaxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aggression:

Aggression (1,523 drugs)

Browse all the conditions that are associated with Aggression:

Aggression (1,965 conditions)

Related publications that referenced our studies

Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on ceftriaxone sodium (the active ingredients of Ceftriaxone) and Ceftriaxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.