Ceftriaxone and Myoclonus - a phase IV clinical study of FDA data

Summary:

Myoclonus is reported as a side effect among people who take Ceftriaxone (ceftriaxone sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Temazepam, and have Sedation.

The phase IV clinical study analyzes which people have Myoclonus when taking Ceftriaxone. It is created by eHealthMe based on reports of 40,872 people who have side effects when taking Ceftriaxone from the FDA, and is updated regularly.

What is Ceftriaxone?

Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.

What is Myoclonus?

Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles) is found to be associated with 759 drugs and 1,139 conditions by eHealthMe. Check the latest studies of Myoclonus.

On Jul, 12, 2026

40,872 people reported to have side effects when taking Ceftriaxone.
Among them, 85 people (0.21%) have Myoclonus.

Among these 85 people:

How long have people been on Ceftriaxone when they have Myoclonus? *

What is the gender of people who have Myoclonus when taking Ceftriaxone? *

female: 47.44 %
male: 52.56 %

What is the age of people who have Myoclonus when taking Ceftriaxone? *

What are other drugs people take besides Ceftriaxone? *

What are other side effects people have besides Myoclonus? *

Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 15 people, 17.65%
Death: 14 people, 16.47%
Encephalopathy (functioning of the brain is affected by some agent or condition): 13 people, 15.29%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 13 people, 15.29%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 13 people, 15.29%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 13 people, 15.29%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 10 people, 11.76%
Drowsiness: 9 people, 10.59%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 9 people, 10.59%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 9 people, 10.59%

What are the existing conditions these people have? *

Sedation: 16 people, 18.82%
Pain: 7 people, 8.24%
Urinary Tract Infection: 7 people, 8.24%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 6 people, 7.06%
Hyperthyroidism (over activity of the thyroid gland): 5 people, 5.88%
Klebsiella Infection: 5 people, 5.88%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 4.71%
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 4 people, 4.71%
Diarrhea: 3 people, 3.53%
Escherichia Infection (bacterial infection by escherichia coli): 3 people, 3.53%

* Approximation only. Some reports may have incomplete information.

Do you take Ceftriaxone and have Myoclonus?

- Check whether Myoclonus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ceftriaxone:

Ceftriaxone (40,991 reports)

Myoclonus treatments and more:

Myoclonus (14,211 reports)

Browse all side effects of Ceftriaxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Myoclonus:

Myoclonus (759 drugs)

Browse all the conditions that are associated with Myoclonus:

Myoclonus (1,139 conditions)

Related publications that referenced our studies

Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on ceftriaxone sodium (the active ingredients of Ceftriaxone) and Ceftriaxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.