Ceftriaxone and Obtunded - a phase IV clinical study of FDA data

Summary:

Obtunded is reported as a side effect among people who take Ceftriaxone (ceftriaxone sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have High blood pressure.

The phase IV clinical study analyzes which people have Obtunded when taking Ceftriaxone. It is created by eHealthMe based on reports of 40,872 people who have side effects when taking Ceftriaxone from the FDA, and is updated regularly.

What is Ceftriaxone?

Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.

What is Obtunded?

Obtunded is found to be associated with 2,493 drugs and 3,172 conditions by eHealthMe. Check the latest studies of Obtunded.

On Oct, 23, 2025

40,872 people reported to have side effects when taking Ceftriaxone.
Among them, 193 people (0.47%) have Obtunded.

Among these 193 people:

How long have people been on Ceftriaxone when they have Obtunded? *

What is the gender of people who have Obtunded when taking Ceftriaxone? *

female: 42.86 %
male: 57.14 %

What is the age of people who have Obtunded when taking Ceftriaxone? *

What are other drugs people take besides Ceftriaxone? *

What are other side effects people have besides Obtunded? *

Fever: 25 people, 12.95%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 24 people, 12.44%
Thrombocytopenia (decrease of platelets in blood): 18 people, 9.33%
Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 17 people, 8.81%
Encephalopathy (functioning of the brain is affected by some agent or condition): 16 people, 8.29%
Anaemia (lack of blood): 16 people, 8.29%
Loss Of Consciousness: 14 people, 7.25%
Diarrhea: 14 people, 7.25%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 14 people, 7.25%
Hypotension (abnormally low blood pressure): 13 people, 6.74%

What are the existing conditions these people have? *

High Blood Pressure: 22 people, 11.40%
Infection: 21 people, 10.88%
Pain: 11 people, 5.70%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 10 people, 5.18%
Type 2 Diabetes: 10 people, 5.18%
Pneumonia Cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses): 8 people, 4.15%
B-Cell Lymphoma Stage Iv (blood cancer affecting b cells stage iv): 8 people, 4.15%
Cough: 7 people, 3.63%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 3.63%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 7 people, 3.63%

* Approximation only. Some reports may have incomplete information.

Do you take Ceftriaxone and have Obtunded?

- Check whether Obtunded is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ceftriaxone:

Ceftriaxone (40,991 reports)

Obtunded treatments and more:

Obtunded (57,420 reports)

Browse all side effects of Ceftriaxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Obtunded:

Browse all the drugs that are associated with Obtunded:

Obtunded (2,493 drugs)

Common conditions associated with Obtunded:

Pain: 2,578 reports
Pain relief: 2,471 reports
Depression: 1,998 reports
Antidepressant therapy: 1,968 reports
Hypertension aggravated: 1,963 reports
Blood pressure - high: 1,924 reports
Ms: 1,512 reports
Acupuncture and pain: 1,424 reports
Rheumatoid arthritis: 1,182 reports
Diabetes mellitus aggravated: 1,167 reports

Browse all the conditions that are associated with Obtunded:

Obtunded (3,172 conditions)

Related publications that referenced our studies

Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on ceftriaxone sodium (the active ingredients of Ceftriaxone) and Ceftriaxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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