1. Home
  2. Analysis
  3. Ceftriaxone
  4. Pain-exacerbated

Ceftriaxone and Pain exacerbated - a phase IV clinical study of FDA data

Summary:

Pain exacerbated is reported as a side effect among people who take Ceftriaxone (ceftriaxone sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have Hiv infection.

The phase IV clinical study analyzes which people have Pain exacerbated when taking Ceftriaxone. It is created by eHealthMe based on reports of 40,872 people who have side effects when taking Ceftriaxone from the FDA, and is updated regularly.

What is Ceftriaxone?

Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.

What is Pain exacerbated?

Pain exacerbated is found to be associated with 4,006 drugs and 2,818 conditions by eHealthMe. Check the latest studies of Pain exacerbated.

On Oct, 23, 2025

40,872 people reported to have side effects when taking Ceftriaxone.
Among them, 667 people (1.63%) have Pain exacerbated.

Could Ceftriaxone cause Pain exacerbated?

Among these 667 people:

How long have people been on Ceftriaxone when they have Pain exacerbated? *

  • < 1 month: 90.53 %
  • 1 - 6 months: 5.26 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 4.21 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pain exacerbated when taking Ceftriaxone? *

  • female: 49.92 %
  • male: 50.08 %

What is the age of people who have Pain exacerbated when taking Ceftriaxone? *

  • 0-1: 0.58 %
  • 2-9: 5.25 %
  • 10-19: 3.11 %
  • 20-29: 8.56 %
  • 30-39: 7.39 %
  • 40-49: 15.95 %
  • 50-59: 17.7 %
  • 60+: 41.44 %

What are other drugs people take besides Ceftriaxone? *

  1. Vancomycin: 142 people, 21.29%
  2. Ondansetron: 91 people, 13.64%
  3. Lasix: 84 people, 12.59%
  4. Zofran: 80 people, 11.99%
  5. Acetaminophen: 79 people, 11.84%
  6. Pantoprazole: 79 people, 11.84%
  7. Heparin: 77 people, 11.54%
  8. Aspirin: 73 people, 10.94%
  9. Truvada: 69 people, 10.34%
  10. Bactrim: 64 people, 9.60%

What are other side effects people have besides Pain exacerbated? *

  1. Stress And Anxiety: 219 people, 32.83%
  2. Fever: 177 people, 26.54%
  3. Emotional Distress: 145 people, 21.74%
  4. Dyspnea (difficult or laboured breathing): 140 people, 20.99%
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 137 people, 20.54%
  6. Nausea (feeling of having an urge to vomit): 122 people, 18.29%
  7. Weakness: 104 people, 15.59%
  8. Diarrhea: 104 people, 15.59%
  9. Joint Pain: 103 people, 15.44%
  10. Fatigue (feeling of tiredness): 101 people, 15.14%

What are the existing conditions these people have? *

  1. Hiv Infection: 95 people, 14.24%
  2. High Blood Pressure: 50 people, 7.50%
  3. Nausea (feeling of having an urge to vomit): 30 people, 4.50%
  4. Fever: 27 people, 4.05%
  5. Immunodeficiency Common Variable: 25 people, 3.75%
  6. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 25 people, 3.75%
  7. Constipation: 25 people, 3.75%
  8. Multiple Myeloma (cancer of the plasma cells): 25 people, 3.75%
  9. Pneumonia: 24 people, 3.60%
  10. High Blood Cholesterol: 22 people, 3.30%

* Approximation only. Some reports may have incomplete information.

Do you take Ceftriaxone and have Pain exacerbated?

- Check whether Pain exacerbated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ceftriaxone:

Pain exacerbated treatments and more:

How severe was Pain exacerbated and when was it recovered:

Expand to all the drugs that have ingredients of ceftriaxone sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Ceftriaxone side effects:

Browse all side effects of Ceftriaxone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Pain exacerbated:

Browse all the drugs that are associated with Pain exacerbated:

Common conditions associated with Pain exacerbated:

Browse all the conditions that are associated with Pain exacerbated:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on ceftriaxone sodium (the active ingredients of Ceftriaxone) and Ceftriaxone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2025 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.