Celebrex and Hepatocellular injury - a phase IV clinical study of FDA data

Summary:

Hepatocellular injury is reported as a side effect among people who take Celebrex (celecoxib), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Morphine, and have Anaesthesia.

The phase IV clinical study analyzes which people have Hepatocellular injury when taking Celebrex. It is created by eHealthMe based on reports of 147,540 people who have side effects when taking Celebrex from the FDA, and is updated regularly.

What is Celebrex?

Celebrex has active ingredients of celecoxib. It is often used in arthritis. eHealthMe is studying from 151,105 Celebrex users. Check the latest studies of Celebrex.

What is Hepatocellular injury?

Hepatocellular injury (liver injury) is found to be associated with 700 drugs and 953 conditions by eHealthMe. Check the latest studies of Hepatocellular injury.

On Jul, 12, 2026

147,540 people reported to have side effects when taking Celebrex.
Among them, 54 people (0.04%) have Hepatocellular injury.

Could Celebrex cause Hepatocellular injury?

Among these 54 people:

How long have people been on Celebrex when they have Hepatocellular injury? *

What is the gender of people who have Hepatocellular injury when taking Celebrex? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Hepatocellular injury when taking Celebrex? *

What are other drugs people take besides Celebrex? *

What are other side effects people have besides Hepatocellular injury? *

Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 19 people, 35.19%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 6 people, 11.11%
Nausea (feeling of having an urge to vomit): 6 people, 11.11%
Overdose: 6 people, 11.11%
Weakness: 5 people, 9.26%
Rashes (redness): 3 people, 5.56%
Drug Level Increased: 3 people, 5.56%
Back Pain: 3 people, 5.56%
Itching: 3 people, 5.56%
Multiple Drug Overdose: 3 people, 5.56%

What are the existing conditions these people have? *

Anaesthesia: 14 people, 25.93%
Ankylosing Spondylitis (type of arthritis affecting the spine): 5 people, 9.26%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 9.26%
Constipation: 4 people, 7.41%
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 3 people, 5.56%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 3.70%
Nausea (feeling of having an urge to vomit): 2 people, 3.70%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 3.70%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 3.70%
Promotion Of Peripheral Circulation: 2 people, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Celebrex and have Hepatocellular injury?

- Check whether Hepatocellular injury is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Celebrex:

Celebrex (151,105 reports)

Browse all side effects of Celebrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatocellular injury:

Hepatocellular injury (700 drugs)

Browse all the conditions that are associated with Hepatocellular injury:

Hepatocellular injury (953 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on celecoxib (the active ingredients of Celebrex) and Celebrex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.