Centrum and Flatulence - a phase IV clinical study of FDA data

Summary:

Flatulence is reported as a side effect among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e), especially for people who are female, 60+ old, also take Fish Oil, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Flatulence when taking Centrum. It is created by eHealthMe based on reports of 33,642 people who have side effects when taking Centrum from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,683 Centrum users. Check the latest studies of Centrum.

What is Flatulence?

Flatulence (flatus expelled through the anus) is found to be associated with 1,804 drugs and 1,883 conditions by eHealthMe. Check the latest studies of Flatulence.

On Jan, 16, 2026

33,642 people reported to have side effects when taking Centrum.
Among them, 316 people (0.94%) have Flatulence.

Among these 316 people:

* Approximation only. Some reports may have incomplete information.

Do you take Centrum and have Flatulence?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Centrum:

Centrum (34,683 reports)

Flatulence treatments and more:

Flatulence (70,665 reports)

How severe was Flatulence and when was it recovered:

Flatulence in Centrum

Expand to all the drugs that have ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e:

Flatulence and drugs with ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (2,290 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Centrum side effects:

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Flatulence:

Browse all the drugs that are associated with Flatulence:

Flatulence (1,804 drugs)

Common conditions associated with Flatulence:

Crohns disease: 2,947 reports
Hypertension: 2,798 reports
Blood pressure - high: 2,792 reports
High cholesterol: 2,686 reports
Diabetic type 2: 2,231 reports
Ulcerative colitis: 1,983 reports
Ms: 1,947 reports
Lipid profile: 1,778 reports
Gastroesophageal reflux disease: 1,739 reports
Lower cholesterol: 1,733 reports

Browse all the conditions that are associated with Flatulence:

Flatulence (1,883 conditions)

Drugs similar to Centrum and Flatulence :

Vitamin d side effect: Flatulence

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Centrum) and Centrum (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.