Cipro and Prothrombin level decreased - a phase IV clinical study of FDA data

Summary:

Prothrombin level decreased is reported as a side effect among people who take Cipro (ciprofloxacin hydrochloride), especially for people who are male, 60+ old, also take Coumadin, and have Cellulitis.

The phase IV clinical study analyzes which people have Prothrombin level decreased when taking Cipro. It is created by eHealthMe based on reports of 32,835 people who have side effects when taking Cipro from the FDA, and is updated regularly.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

What is Prothrombin level decreased?

Prothrombin level decreased is found to be associated with 202 drugs and 466 conditions by eHealthMe. Check the latest studies of Prothrombin level decreased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

32,835 people reported to have side effects when taking Cipro.
Among them, 14 people (0.04%) have Prothrombin level decreased.

Could Cipro cause Prothrombin level decreased?

Among these 14 people:

What is the gender of people who have Prothrombin level decreased when taking Cipro? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Prothrombin level decreased when taking Cipro? *

What are other drugs people take besides Cipro? *

Coumadin: 6 people, 42.86%
Acetaminophen: 2 people, 14.29%
Furosemide: 2 people, 14.29%
Warfarin Sodium: 2 people, 14.29%
Lasix: 1 person, 7.14%
Acetaminophen And Codeine Phosphate: 1 person, 7.14%
Allopurinol: 1 person, 7.14%
Atenolol: 1 person, 7.14%
Benadryl: 1 person, 7.14%
Digoxin: 1 person, 7.14%

What are other side effects people have besides Prothrombin level decreased? *

International Normalised Ratio Increased: 5 people, 35.71%
Haemorrhagic Stroke (stroke caused by the rupture of a blood vessel in the brain): 1 person, 7.14%
Cerebral Oedema (swelling of brain): 1 person, 7.14%
Cardiac Failure Congestive: 1 person, 7.14%

What are the existing conditions these people have? *

Chronic Obstructive Airways Disease: 1 person, 7.14%
Cellulitis (infection under the skin): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Cipro and have Prothrombin level decreased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cipro:

Cipro (35,126 reports)

Browse all side effects of Cipro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Prothrombin level decreased:

Prothrombin level decreased (202 drugs)

Browse all the conditions that are associated with Prothrombin level decreased:

Prothrombin level decreased (466 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ciprofloxacin hydrochloride (the active ingredients of Cipro) and Cipro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.