Ciprofloxacin and Foot amputation - a phase IV clinical study of FDA data

Summary:

Foot amputation is reported as a side effect among people who take Ciprofloxacin (ciprofloxacin), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Ceftriaxone, and have Nausea.

The phase IV clinical study analyzes which people have Foot amputation when taking Ciprofloxacin. It is created by eHealthMe based on reports of 21,064 people who have side effects when taking Ciprofloxacin from the FDA, and is updated regularly.

What is Ciprofloxacin?

Ciprofloxacin has active ingredients of ciprofloxacin. It is often used in urinary tract infection. eHealthMe is studying from 22,256 Ciprofloxacin users. Check the latest studies of Ciprofloxacin.

What is Foot amputation?

Foot amputation (loss of foot) is found to be associated with 128 drugs and 204 conditions by eHealthMe. Check the latest studies of Foot amputation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

21,064 people reported to have side effects when taking Ciprofloxacin.
Among them, 12 people (0.06%) have Foot amputation.

Could Ciprofloxacin cause Foot amputation?

Among these 12 people:

How long have people been on Ciprofloxacin when they have Foot amputation? *

What is the gender of people who have Foot amputation when taking Ciprofloxacin? *

female: 36.36 %
male: 63.64 %

What is the age of people who have Foot amputation when taking Ciprofloxacin? *

What are other drugs people take besides Ciprofloxacin? *

What are other side effects people have besides Foot amputation? *

Nausea (feeling of having an urge to vomit): 8 people, 66.67%
Drug Ineffective: 6 people, 50.00%
Pathogen Resistance: 6 people, 50.00%
Nausea And Vomiting: 6 people, 50.00%
Fall: 6 people, 50.00%
Hypokalemia (low potassium): 6 people, 50.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 50.00%
Blood Creatinine Increased: 4 people, 33.33%
Drug Resistance (reduction in effectiveness of a drug): 3 people, 25.00%
Rashes (redness): 3 people, 25.00%

What are the existing conditions these people have? *

Streptococcal Infection: 6 people, 50.00%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 6 people, 50.00%
Nausea (feeling of having an urge to vomit): 6 people, 50.00%
Staphylococcal Infection (an infection with staphylococcus bacteria): 4 people, 33.33%
Wound Infection Staphylococcal: 3 people, 25.00%
Wound Infection Pseudomonas: 3 people, 25.00%
Wound: 3 people, 25.00%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 25.00%
Osteomyelitis Bacterial (infection of bone by bacteria): 3 people, 25.00%
Osteomyelitis (infection of bone): 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Ciprofloxacin and have Foot amputation?

- Check whether Foot amputation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ciprofloxacin:

Ciprofloxacin (22,256 reports)

Foot amputation treatments and more:

Foot amputation (1,761 reports)

Browse all side effects of Ciprofloxacin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Foot amputation:

Foot amputation (128 drugs)

Browse all the conditions that are associated with Foot amputation:

Foot amputation (204 conditions)

Related publications that referenced our studies

Bolognesi M, Bolognesi D, "Medicine Ciprofloxacin-induced paroxysmal atrial fibrillation", , 2014 Mar .
Bolognesi M, Bolognesi D, "Ciprofloxacin-induced paroxysmal atrial fibrilation", OA Case Reports, 2012 Jan .
Bolognesi M, Bolognesi D, "Medicine Ciprofloxacin-induced paroxysmal atrial fibrillation", , 2014 Mar .
Bolognesi M, Bolognesi D, "Ciprofloxacin-induced paroxysmal atrial fibrilation", OA Case Reports, 2012 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on ciprofloxacin (the active ingredients of Ciprofloxacin) and Ciprofloxacin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.