Clonazepam and Extremity contracture - a phase IV clinical study of FDA data

Summary:

Extremity contracture is reported as a side effect among people who take Clonazepam (clonazepam), especially for people who are female, 30-39 old, also take Magnevist, and have Pain.

The phase IV clinical study analyzes which people have Extremity contracture when taking Clonazepam. It is created by eHealthMe based on reports of 140,365 people who have side effects when taking Clonazepam from the FDA, and is updated regularly.

What is Clonazepam?

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,271 Clonazepam users. Check the latest studies of Clonazepam.

What is Extremity contracture?

Extremity contracture (permanent shortening of a muscle or joint of arms and legs) is found to be associated with 206 drugs and 258 conditions by eHealthMe. Check the latest studies of Extremity contracture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

140,365 people reported to have side effects when taking Clonazepam.
Among them, 14 people (0.01%) have Extremity contracture.

Could Clonazepam cause Extremity contracture?

Among these 14 people:

What is the gender of people who have Extremity contracture when taking Clonazepam? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Extremity contracture when taking Clonazepam? *

What are other drugs people take besides Clonazepam? *

What are other side effects people have besides Extremity contracture? *

Pain: 6 people, 42.86%
Fatigue (feeling of tiredness): 5 people, 35.71%
Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 5 people, 35.71%
Skin Hypertrophy (skin cells enlarges): 5 people, 35.71%
Joint Contracture (a permanent shortening of a muscle or joint): 4 people, 28.57%
Skin Induration (an abnormally hard spot or area on the skin): 4 people, 28.57%
Joint Pain: 4 people, 28.57%
Joint Range Of Motion Decreased (disease of joint movement): 4 people, 28.57%
Memory Loss: 4 people, 28.57%
Mobility Decreased (ability to move is reduced): 4 people, 28.57%

What are the existing conditions these people have? *

Pain: 5 people, 35.71%
Abdominal Pain: 3 people, 21.43%
Nuclear Magnetic Resonance Imaging Brain: 3 people, 21.43%
Neuropathy Peripheral (surface nerve damage): 3 people, 21.43%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 21.43%
Drug Exposure During Pregnancy: 2 people, 14.29%
Renal Cell Carcinoma (a kidney cancer): 2 people, 14.29%
Bacteraemia (presence of bacteria in the blood): 2 people, 14.29%
Palmar-Plantar Erythrodysaesthesia Syndrome (hand-foot syndrome): 2 people, 14.29%
Blindness Unilateral: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Clonazepam and have Extremity contracture?

- Check whether Extremity contracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clonazepam:

Clonazepam (146,271 reports)

Browse all side effects of Clonazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Extremity contracture:

Extremity contracture (206 drugs)

Browse all the conditions that are associated with Extremity contracture:

Extremity contracture (258 conditions)

Related publications that referenced our studies

McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on clonazepam (the active ingredients of Clonazepam) and Clonazepam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.