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Clopidogrel bisulfate and Brain herniation - a phase IV clinical study of FDA data

Summary:

Brain herniation is reported as a side effect among people who take Clopidogrel bisulfate (clopidogrel bisulfate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ativan, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Brain herniation when taking Clopidogrel bisulfate. It is created by eHealthMe based on reports of 17,862 people who have side effects when taking Clopidogrel bisulfate from the FDA, and is updated regularly.

What is Clopidogrel bisulfate?

Clopidogrel bisulfate has active ingredients of clopidogrel bisulfate. It is often used in blood clots. eHealthMe is studying from 18,075 Clopidogrel bisulfate users. Check the latest studies of Clopidogrel bisulfate.

What is Brain herniation?

Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull) is found to be associated with 337 drugs and 975 conditions by eHealthMe. Check the latest studies of Brain herniation.

On Jul, 15, 2026

17,862 people reported to have side effects when taking Clopidogrel bisulfate.
Among them, 60 people (0.34%) have Brain herniation.

Could Clopidogrel bisulfate cause Brain herniation?

Among these 60 people:

How long have people been on Clopidogrel bisulfate when they have Brain herniation? *

  • < 1 month: 75 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 25 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Brain herniation when taking Clopidogrel bisulfate? *

  • female: 63.27 %
  • male: 36.73 %

What is the age of people who have Brain herniation when taking Clopidogrel bisulfate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 2.04 %
  • 50-59: 2.04 %
  • 60+: 95.92 %

What are other drugs people take besides Clopidogrel bisulfate? *

  1. Ativan: 31 people, 51.67%
  2. Cymbalta: 30 people, 50.00%
  3. Aspirin: 28 people, 46.67%
  4. Oxycodone: 25 people, 41.67%
  5. Methotrexate: 17 people, 28.33%
  6. Topiramate: 17 people, 28.33%
  7. Phenytoin: 17 people, 28.33%
  8. Gabapentin: 17 people, 28.33%
  9. Prednisone: 17 people, 28.33%
  10. Propofol: 17 people, 28.33%

What are other side effects people have besides Brain herniation? *

  1. Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 34 people, 56.67%
  2. Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 31 people, 51.67%
  3. Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 31 people, 51.67%
  4. Ascites (accumulation of fluid in the abdominal cavity): 31 people, 51.67%
  5. Ischaemic Cerebral Infarction (ischemic stroke resulting from a disturbance in the blood vessels supplying blood to the brain): 31 people, 51.67%
  6. Subdural Haematoma (blood collects between the skull and the surface of the brain): 12 people, 20.00%
  7. Consciousness - Decreased: 11 people, 18.33%
  8. Cerebral Haemorrhage (bleeding within the brain): 10 people, 16.67%
  9. Brain Stem Syndrome: 10 people, 16.67%
  10. Head Injury: 9 people, 15.00%

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 6.67%
  2. Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 2 people, 3.33%
  3. High Blood Pressure: 2 people, 3.33%
  4. Urination - Excessive Volume: 1 person, 1.67%
  5. Clonus (series of involuntary, rhythmic, muscular contractions and relaxations): 1 person, 1.67%
  6. Anaesthesia: 1 person, 1.67%
  7. Arrhythmias (irregular heartbeat): 1 person, 1.67%
  8. Blood Glucose Decreased: 1 person, 1.67%
  9. Cardiac Failure Congestive: 1 person, 1.67%
  10. Cerebral Artery Occlusion (blockage of blood vessel of brain by fat or clot): 1 person, 1.67%

* Approximation only. Some reports may have incomplete information.

Do you take Clopidogrel bisulfate and have Brain herniation?

- Check whether Brain herniation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clopidogrel bisulfate:

Brain herniation treatments and more:

How severe was Brain herniation and when was it recovered:

Expand to all the drugs that have ingredients of clopidogrel bisulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clopidogrel bisulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Brain herniation:

Browse all the conditions that are associated with Brain herniation:

How the study uses the data?

The study uses data from the FDA. It is based on clopidogrel bisulfate (the active ingredients of Clopidogrel bisulfate) and Clopidogrel bisulfate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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