Clopidogrel and Type iv hypersensitivity reaction - a phase IV clinical study of FDA data
Summary:
Type iv hypersensitivity reaction is reported as a side effect among people who take Clopidogrel (clopidogrel), especially for people who are male, 60+ old, also take Acetylsalicylic Acid, and have High blood pressure.
The phase IV clinical study analyzes which people have Type iv hypersensitivity reaction when taking Clopidogrel. It is created by eHealthMe based on reports of 91,038 people who have side effects when taking Clopidogrel from the FDA, and is updated regularly.
What is Clopidogrel?
Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.
What is Type iv hypersensitivity reaction?
Type iv hypersensitivity reaction (delayed type hypersensitivity as the reaction takes two to three days to develop) is found to be associated with 193 drugs and 415 conditions by eHealthMe. Check the latest studies of Type iv hypersensitivity reaction.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
91,038 people reported to have side effects when taking Clopidogrel.
Among them, 12 people (0.01%) have Type iv hypersensitivity reaction.

Among these 12 people:
What is the gender of people who have Type iv hypersensitivity reaction when taking Clopidogrel? *
- female: 36.36 %
- male: 63.64 %
What is the age of people who have Type iv hypersensitivity reaction when taking Clopidogrel? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 100 %
What are other drugs people take besides Clopidogrel? *
- Acetylsalicylic Acid: 6 people, 50.00%
- Aspirin: 4 people, 33.33%
- Methenamine Hippurate: 2 people, 16.67%
- Carvedilol: 2 people, 16.67%
- Irbesartan: 2 people, 16.67%
- Isosorbide Mononitrate: 2 people, 16.67%
- Sulfasalazine: 2 people, 16.67%
- Ticagrelor: 2 people, 16.67%
- Ramipril: 2 people, 16.67%
- Simvastatin: 2 people, 16.67%
What are other side effects people have besides Type iv hypersensitivity reaction? *
- Joint Pain: 4 people, 33.33%
- Rash Erythematous (redness of the skin): 3 people, 25.00%
- Peripheral Swelling: 3 people, 25.00%
- Lip Swelling: 3 people, 25.00%
- Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 16.67%
- Mesenteric Panniculitis (a rare benign inflammatory condition of unknown origin that affects the mesenteric fat): 2 people, 16.67%
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 16.67%
- Fever: 2 people, 16.67%
- Meningitis Aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed): 2 people, 16.67%
- Oedema Peripheral (superficial swelling): 2 people, 16.67%
What are the existing conditions these people have? *
- High Blood Pressure: 3 people, 25.00%
- Seronegative Arthritis (a joint disease negative for rheumatoid arthritis): 2 people, 16.67%
- Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 8.33%
- Urinary Tract Infection: 1 person, 8.33%
- Stable Angina (a constant chest pain): 1 person, 8.33%
- Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 1 person, 8.33%
- Inflammatory Bowel Disease: 1 person, 8.33%
- High Blood Cholesterol: 1 person, 8.33%
- Asthma: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Clopidogrel and have Type iv hypersensitivity reaction?
- Check whether Type iv hypersensitivity reaction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Clopidogrel:
- Clopidogrel (92,160 reports)
Type iv hypersensitivity reaction treatments and more:
- Type iv hypersensitivity reaction (2,728 reports)
How severe was Type iv hypersensitivity reaction and when was it recovered:
Expand to all the drugs that have ingredients of clopidogrel:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clopidogrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Type iv hypersensitivity reaction:
- Type iv hypersensitivity reaction (193 drugs)
Browse all the conditions that are associated with Type iv hypersensitivity reaction:
- Type iv hypersensitivity reaction (415 conditions)
Related publications that referenced our studies
- Lai SW, Lin CL, Liao KF, "Actively using clopidogrel correlates with an increased risk of acute pancreatitis in Taiwan", International journal of cardiology, 2015 Mar .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
- Lai SW, Lin CL, Liao KF, "Actively using clopidogrel correlates with an increased risk of acute pancreatitis in Taiwan", International journal of cardiology, 2015 Mar .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on clopidogrel (the active ingredients of Clopidogrel) and Clopidogrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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