Clopidogrel and Vascular encephalopathy - a phase IV clinical study of FDA data

Summary:

Vascular encephalopathy is reported as a side effect among people who take Clopidogrel (clopidogrel), especially for people who are female, 60+ old, also take Amlodipine, and have Acute coronary syndrome.

The phase IV clinical study analyzes which people have Vascular encephalopathy when taking Clopidogrel. It is created by eHealthMe based on reports of 91,038 people who have side effects when taking Clopidogrel from the FDA, and is updated regularly.

What is Clopidogrel?

Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.

What is Vascular encephalopathy?

Vascular encephalopathy (vascular disorder or disease of the brain) is found to be associated with 59 drugs and 131 conditions by eHealthMe. Check the latest studies of Vascular encephalopathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

91,038 people reported to have side effects when taking Clopidogrel.
Among them, 26 people (0.03%) have Vascular encephalopathy.

Could Clopidogrel cause Vascular encephalopathy?

Among these 26 people:

What is the gender of people who have Vascular encephalopathy when taking Clopidogrel? *

female: 79.17 %
male: 20.83 %

What is the age of people who have Vascular encephalopathy when taking Clopidogrel? *

What are other drugs people take besides Clopidogrel? *

What are other side effects people have besides Vascular encephalopathy? *

High Blood Pressure: 18 people, 69.23%
Ventricular Extrasystoles (premature cardiac contraction): 16 people, 61.54%
Acute Myocardial Infarction (acute heart attack): 16 people, 61.54%
Arrhythmias (irregular heartbeat): 16 people, 61.54%
Atherosclerosis (disorder of the arteries): 16 people, 61.54%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 16 people, 61.54%
Chest Pain: 16 people, 61.54%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 16 people, 61.54%
Dyspnea Exertional: 16 people, 61.54%
Type 2 Diabetes: 16 people, 61.54%

What are the existing conditions these people have? *

Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 12 people, 46.15%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 3 people, 11.54%
Pericarditis - After Heart Attack (inflammation of the pericardium-after heart attack): 3 people, 11.54%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 3 people, 11.54%
High Blood Pressure: 2 people, 7.69%
Depression: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Clopidogrel and have Vascular encephalopathy?

- Check whether Vascular encephalopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clopidogrel:

Clopidogrel (92,160 reports)

Browse all side effects of Clopidogrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vascular encephalopathy:

Vascular encephalopathy (59 drugs)

Browse all the conditions that are associated with Vascular encephalopathy:

Vascular encephalopathy (131 conditions)

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on clopidogrel (the active ingredients of Clopidogrel) and Clopidogrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.