Clopra and Ligament rupture - a phase IV clinical study of FDA data

Summary:

Ligament rupture is reported as a side effect among people who take Clopra (metoclopramide hydrochloride), especially for people who are female, 40-49 old, also take Paxil, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Ligament rupture when taking Clopra. It is created by eHealthMe based on reports of 80,974 people who have side effects when taking Clopra from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Ligament rupture?

Ligament rupture (tear in ligament) is found to be associated with 502 drugs and 550 conditions by eHealthMe. Check the latest studies of Ligament rupture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

80,974 people reported to have side effects when taking Clopra.
Among them, 21 people (0.03%) have Ligament rupture.

Among these 21 people:

What is the gender of people who have Ligament rupture when taking Clopra? *

female: 68.42 %
male: 31.58 %

What is the age of people who have Ligament rupture when taking Clopra? *

What are other drugs people take besides Clopra? *

What are other side effects people have besides Ligament rupture? *

Pain: 16 people, 76.19%
Stress And Anxiety: 16 people, 76.19%
Nausea (feeling of having an urge to vomit): 15 people, 71.43%
Nausea And Vomiting: 15 people, 71.43%
Fall: 15 people, 71.43%
Osteonecrosis Of Jaw (death of bone of jaw): 14 people, 66.67%
Depression: 14 people, 66.67%
Back Pain: 14 people, 66.67%
Spinal Osteoarthritis (joint cartilage loss in spine): 14 people, 66.67%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 13 people, 61.90%

What are the existing conditions these people have? *

Breast Cancer Metastatic: 8 people, 38.10%
Irritable Bowel Syndrome: 7 people, 33.33%
Prostate Cancer Metastatic: 4 people, 19.05%
Stress And Anxiety: 2 people, 9.52%
Hiv Infection: 2 people, 9.52%
Hepatitis B: 2 people, 9.52%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.76%
Nausea And Vomiting: 1 person, 4.76%
Nausea (feeling of having an urge to vomit): 1 person, 4.76%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Clopra and have Ligament rupture?

- Check whether Ligament rupture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clopra:

Clopra (81,430 reports)

Browse all side effects of Clopra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ligament rupture:

Ligament rupture (502 drugs)

Browse all the conditions that are associated with Ligament rupture:

Ligament rupture (550 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride (the active ingredients of Clopra) and Clopra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.