Codeine sulfate and Lumbar spine flattening - a phase IV clinical study of FDA data

Summary:

Lumbar spine flattening is reported as a side effect among people who take Codeine sulfate (codeine sulfate), especially for people who are female, 40-49 old, also take Lopressor, and have Bone loss.

The phase IV clinical study analyzes which people have Lumbar spine flattening when taking Codeine sulfate. It is created by eHealthMe based on reports of 4,237 people who have side effects when taking Codeine sulfate from the FDA, and is updated regularly.

What is Codeine sulfate?

Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 4,510 Codeine sulfate users. Check the latest studies of Codeine sulfate.

What is Lumbar spine flattening?

Lumbar spine flattening (flatten the curve of the lower spine) is found to be associated with 65 drugs and 83 conditions by eHealthMe. Check the latest studies of Lumbar spine flattening.



On Jul, 20, 2026

4,237 people reported to have side effects when taking Codeine sulfate.
Among them, 13 people (0.31%) have Lumbar spine flattening.

Could Codeine sulfate cause Lumbar spine flattening?

Among these 13 people:

What is the gender of people who have Lumbar spine flattening when taking Codeine sulfate? *

  • female: 53.85 %
  • male: 46.15 %

What is the age of people who have Lumbar spine flattening when taking Codeine sulfate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 87.5 %
  • 50-59: 0.0 %
  • 60+: 12.5 %

What are other drugs people take besides Codeine sulfate? *

  1. Lopressor: 13 people, 100.00%
  2. Levaquin: 10 people, 76.92%
  3. Flomax: 10 people, 76.92%
  4. Acetaminophen: 7 people, 53.85%
  5. Colace: 7 people, 53.85%
  6. Zoloft: 7 people, 53.85%
  7. Lisinopril: 7 people, 53.85%
  8. Lortab: 7 people, 53.85%
  9. Lunesta: 7 people, 53.85%
  10. Femara: 7 people, 53.85%

What are other side effects people have besides Lumbar spine flattening? *

  1. Renal Cyst (kidney cyst): 13 people, 100.00%
  2. Dyspnea (difficult or laboured breathing): 13 people, 100.00%
  3. Intervertebral Disc Protrusion (spinal disc protrusion): 13 people, 100.00%
  4. Intervertebral Disc Degeneration (spinal disc degeneration): 13 people, 100.00%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 13 people, 100.00%
  6. Hypoaesthesia (reduced sense of touch or sensation): 13 people, 100.00%
  7. Osteonecrosis Of Jaw (death of bone of jaw): 13 people, 100.00%
  8. Scoliosis (a medical condition in which a person's spine is curved from side to side): 13 people, 100.00%
  9. Exposed Bone In Jaw: 13 people, 100.00%
  10. Joint Pain: 12 people, 92.31%

What are the existing conditions these people have? *

  1. Bone Loss: 7 people, 53.85%
  2. High Blood Pressure: 6 people, 46.15%
  3. Metastasis (spreadable cancer to other organ from origin): 4 people, 30.77%

* Approximation only. Some reports may have incomplete information.

Do you take Codeine sulfate and have Lumbar spine flattening?

- Check whether Lumbar spine flattening is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Codeine sulfate:

Lumbar spine flattening treatments and more:

How severe was Lumbar spine flattening and when was it recovered:

Expand to all the drugs that have ingredients of codeine sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Codeine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lumbar spine flattening:

Browse all the conditions that are associated with Lumbar spine flattening:


How the study uses the data?

The study uses data from the FDA. It is based on codeine sulfate (the active ingredients of Codeine sulfate) and Codeine sulfate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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