Coreg and Coma - a phase IV clinical study of FDA data

Summary:

Coma is reported as a side effect among people who take Coreg (carvedilol), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Lasix, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Coma when taking Coreg. It is created by eHealthMe based on reports of 48,155 people who have side effects when taking Coreg from the FDA, and is updated regularly.

What is Coreg?

Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,577 Coreg users. Check the latest studies of Coreg.

What is Coma?

Coma (state of unconsciousness lasting more than six hours) is found to be associated with 2,889 drugs and 3,170 conditions by eHealthMe. Check the latest studies of Coma.

On Oct, 09, 2025

48,155 people reported to have side effects when taking Coreg.
Among them, 113 people (0.23%) have Coma.

Among these 113 people:

* Approximation only. Some reports may have incomplete information.

Do you take Coreg and have Coma?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Coreg:

Coreg (49,577 reports)

Coma treatments and more:

Coma (57,420 reports)

How severe was Coma and when was it recovered:

Coma in Coreg

Expand to all the drugs that have ingredients of carvedilol:

Coma and drugs with ingredients of carvedilol (384 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Coreg side effects:

Browse all side effects of Coreg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Coma:

Browse all the drugs that are associated with Coma:

Coma (2,889 drugs)

Common conditions associated with Coma:

Pain exacerbated: 2,578 reports
Hypnosis and pain: 2,471 reports
Depression aggravated: 1,998 reports
Antidepressant therapy: 1,968 reports
Hypertension aggravated: 1,963 reports
Blood pressure increased: 1,924 reports
Multiple sclerosis: 1,512 reports
Acupuncture and pain: 1,424 reports
Arthritis - rheumatoid: 1,182 reports
Diabetes mellitus aggravated: 1,167 reports

Browse all the conditions that are associated with Coma:

Coma (3,170 conditions)

Drugs similar to Coreg and Coma :

Related publications that referenced our studies

Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on carvedilol (the active ingredients of Coreg) and Coreg (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.