Cortril and Pain exacerbated - a phase IV clinical study of FDA data

Summary:

Pain exacerbated is reported as a side effect among people who take Cortril (hydrocortisone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Remodulin, and have Adrenal insufficiency.

The phase IV clinical study analyzes which people have Pain exacerbated when taking Cortril. It is created by eHealthMe based on reports of 1,715 people who have side effects when taking Cortril from the FDA, and is updated regularly.

What is Cortril?

Cortril has active ingredients of hydrocortisone. eHealthMe is studying from 1,715 Cortril users. Check the latest studies of Cortril.

What is Pain exacerbated?

Pain exacerbated is found to be associated with 3,987 drugs and 3,018 conditions by eHealthMe. Check the latest studies of Pain exacerbated.



On Jul, 10, 2026

1,715 people reported to have side effects when taking Cortril.
Among them, 17 people (0.99%) have Pain exacerbated.

Could Cortril cause Pain exacerbated?

Among these 17 people:

How long have people been on Cortril when they have Pain exacerbated? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pain exacerbated when taking Cortril? *

  • female: 70.59 %
  • male: 29.41 %

What is the age of people who have Pain exacerbated when taking Cortril? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5.88 %
  • 30-39: 23.53 %
  • 40-49: 23.53 %
  • 50-59: 0.0 %
  • 60+: 47.06 %

What are other drugs people take besides Cortril? *

  1. Lyrica: 8 people, 47.06%
  2. Remodulin: 8 people, 47.06%
  3. Adempas: 5 people, 29.41%
  4. Adcirca: 4 people, 23.53%
  5. Flolan: 4 people, 23.53%
  6. Cymbalta: 4 people, 23.53%
  7. Opsumit: 4 people, 23.53%
  8. Lasix: 4 people, 23.53%
  9. Revatio: 4 people, 23.53%
  10. Samsca: 4 people, 23.53%

What are other side effects people have besides Pain exacerbated? *

  1. Fever: 8 people, 47.06%
  2. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 7 people, 41.18%
  3. Back Pain: 6 people, 35.29%
  4. Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 4 people, 23.53%
  5. Rashes (redness): 4 people, 23.53%
  6. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 4 people, 23.53%
  7. Injection Site Pain: 4 people, 23.53%
  8. Infusion Site Swelling: 4 people, 23.53%
  9. Headache (pain in head): 4 people, 23.53%
  10. Eosinophilia (eosinophil count in the peripheral blood exceeds): 4 people, 23.53%

What are the existing conditions these people have? *

  1. Diarrhea: 8 people, 47.06%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 47.06%
  3. Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 8 people, 47.06%
  4. Irritable Bowel Syndrome: 4 people, 23.53%
  5. Iron Deficiency Anaemia: 4 people, 23.53%
  6. Anaemia (lack of blood): 4 people, 23.53%
  7. Hypokalemia (low potassium): 4 people, 23.53%
  8. Cardiac Failure Chronic: 4 people, 23.53%
  9. Malignant Melanoma Stage Iv (the cancer has spread to other places in the body, such as the lung, liver, brain, bone, soft tissue, or gastrointestinal (gi) tract. cancer may have spread to places in the skin far away from where it first started): 3 people, 17.65%
  10. Diabetes: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Cortril and have Pain exacerbated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cortril:

Pain exacerbated treatments and more:

How severe was Pain exacerbated and when was it recovered:

Expand to all the drugs that have ingredients of hydrocortisone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cortril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain exacerbated:

Browse all the conditions that are associated with Pain exacerbated:


How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Cortril) and Cortril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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