Creon and Dermatitis - a phase IV clinical study of FDA data

Summary:

Dermatitis is reported as a side effect among people who take Creon (pancrelipase (amylase;lipase;protease)), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Protonix, and have Pain.

The phase IV clinical study analyzes which people have Dermatitis when taking Creon. It is created by eHealthMe based on reports of 29,220 people who have side effects when taking Creon from the FDA, and is updated regularly.

What is Creon?

Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.

What is Dermatitis?

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it) is found to be associated with 1,539 drugs and 1,232 conditions by eHealthMe. Check the latest studies of Dermatitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

29,220 people reported to have side effects when taking Creon.
Among them, 21 people (0.07%) have Dermatitis.

Among these 21 people:

How long have people been on Creon when they have Dermatitis? *

What is the gender of people who have Dermatitis when taking Creon? *

female: 41.18 %
male: 58.82 %

What is the age of people who have Dermatitis when taking Creon? *

What are other drugs people take besides Creon? *

What are other side effects people have besides Dermatitis? *

Stress And Anxiety: 9 people, 42.86%
Pain: 5 people, 23.81%
Hypotension (abnormally low blood pressure): 4 people, 19.05%
Arrhythmias (irregular heartbeat): 4 people, 19.05%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 19.05%
Thinking Abnormal: 4 people, 19.05%
Hot Flush (sudden feelings of heat): 4 people, 19.05%
Feeling Cold: 4 people, 19.05%
Gastrointestinal Tract Adenoma (a benign tumour (-oma) of glandular origin in digestive tract): 3 people, 14.29%
Oesophageal Achalasia (difficulty swallowing, food sticking in the oesophagus): 3 people, 14.29%

What are the existing conditions these people have? *

Pain: 10 people, 47.62%
Abdominal Discomfort: 6 people, 28.57%
Nausea (feeling of having an urge to vomit): 6 people, 28.57%
Abdominal Pain Upper: 5 people, 23.81%
Stress And Anxiety: 5 people, 23.81%
Flatulence (flatus expelled through the anus): 5 people, 23.81%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 5 people, 23.81%
Asthma: 4 people, 19.05%
Depression: 4 people, 19.05%
Neuralgia (pain in one or more nerves): 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Creon and have Dermatitis?

- Check whether Dermatitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Creon:

Creon (29,489 reports)

Dermatitis treatments and more:

Dermatitis (30,577 reports)

How severe was Dermatitis and when was it recovered:

Dermatitis in Creon

Expand to all the drugs that have ingredients of pancrelipase (amylase;lipase;protease):

Dermatitis and drugs with ingredients of pancrelipase (amylase;lipase;protease)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Creon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dermatitis:

Dermatitis (1,539 drugs)

Browse all the conditions that are associated with Dermatitis:

Dermatitis (1,232 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) (the active ingredients of Creon) and Creon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.