Cymbalta and Maternal exposure before pregnancy - a phase IV clinical study of FDA data

Summary:

Maternal exposure before pregnancy is reported as a side effect among people who take Cymbalta (duloxetine hydrochloride), especially for people who are 30-39 old, have been taking the drug for 2 - 5 years also take Calcium, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Maternal exposure before pregnancy when taking Cymbalta. It is created by eHealthMe based on reports of 145,249 people who have side effects when taking Cymbalta from the FDA, and is updated regularly.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 154,973 Cymbalta users. Check the latest studies of Cymbalta.

What is Maternal exposure before pregnancy?

Maternal exposure before pregnancy (use of substance before pregnancy) is found to be associated with 274 drugs and 349 conditions by eHealthMe. Check the latest studies of Maternal exposure before pregnancy.

On Jul, 10, 2026

145,249 people reported to have side effects when taking Cymbalta.
Among them, 21 people (0.01%) have Maternal exposure before pregnancy.

Could Cymbalta cause Maternal exposure before pregnancy?

Among these 21 people:

How long have people been on Cymbalta when they have Maternal exposure before pregnancy? *

What is the age of people who have Maternal exposure before pregnancy when taking Cymbalta? *

What are other drugs people take besides Cymbalta? *

Calcium: 5 people, 23.81%
Fish Oil: 4 people, 19.05%
Copaxone: 3 people, 14.29%
Vitamin D: 3 people, 14.29%
Ocrevus: 3 people, 14.29%
Methylprednisolone Sodium Succinate: 2 people, 9.52%
Seroquel: 2 people, 9.52%
Colace: 2 people, 9.52%
Coq: 2 people, 9.52%
Lantus: 2 people, 9.52%

What are other side effects people have besides Maternal exposure before pregnancy? *

Maternal Exposure During Pregnancy (use of substance during pregnancy): 5 people, 23.81%
Pulmonary Oedema (fluid accumulation in the lungs): 3 people, 14.29%
Kidney Infection: 3 people, 14.29%
Injury: 3 people, 14.29%
Hypoaesthesia (reduced sense of touch or sensation): 3 people, 14.29%
Pneumonia: 3 people, 14.29%
Eclampsia (acute and life-threatening complication of pregnancy): 3 people, 14.29%
Memory Loss: 3 people, 14.29%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 14.29%
Cardiac Failure: 3 people, 14.29%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 28.57%
Pain: 4 people, 19.05%
Fungal Infection: 3 people, 14.29%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 14.29%
Joint Pain: 3 people, 14.29%
Headache (pain in head): 3 people, 14.29%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 9.52%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 4.76%
Anaemia (lack of blood): 1 person, 4.76%
Arrhythmias (irregular heartbeat): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Cymbalta and have Maternal exposure before pregnancy?

- Check whether Maternal exposure before pregnancy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Cymbalta:

Cymbalta (154,973 reports)

Browse all side effects of Cymbalta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Maternal exposure before pregnancy:

Maternal exposure before pregnancy (274 drugs)

Browse all the conditions that are associated with Maternal exposure before pregnancy:

Maternal exposure before pregnancy (349 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on duloxetine hydrochloride (the active ingredients of Cymbalta) and Cymbalta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.