Depo-provera and Labyrinthitis - a phase IV clinical study of FDA data

Summary:

Labyrinthitis is reported as a side effect among people who take Depo-provera (medroxyprogesterone acetate), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Cymbalta, and have Anaemia.

The phase IV clinical study analyzes which people have Labyrinthitis when taking Depo-provera. It is created by eHealthMe based on reports of 15,804 people who have side effects when taking Depo-provera from the FDA, and is updated regularly.

What is Depo-provera?

Depo-provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 17,093 Depo-provera users. Check the latest studies of Depo-provera.

What is Labyrinthitis?

Labyrinthitis (inflammation of the labyrinth or inner ear) is found to be associated with 413 drugs and 1,021 conditions by eHealthMe. Check the latest studies of Labyrinthitis.



On Jul, 06, 2026

15,804 people reported to have side effects when taking Depo-provera.
Among them, 17 people (0.11%) have Labyrinthitis.

Could Depo-provera cause Labyrinthitis?

Among these 17 people:

How long have people been on Depo-provera when they have Labyrinthitis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Labyrinthitis when taking Depo-provera? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Labyrinthitis when taking Depo-provera? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 45.45 %
  • 30-39: 27.27 %
  • 40-49: 27.27 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Depo-provera? *

  1. Ultracet: 1 person, 5.88%
  2. Feldene: 1 person, 5.88%
  3. Enbrel: 1 person, 5.88%
  4. Cymbalta: 1 person, 5.88%

What are other side effects people have besides Labyrinthitis? *

  1. Amenorrhea (absence of a menstrual period in a woman of reproductive age): 10 people, 58.82%
  2. Weight Increased: 5 people, 29.41%
  3. Injection Site Pain: 3 people, 17.65%
  4. Vaginal Bleeding Between Periods: 3 people, 17.65%
  5. Injection Site Erythema (redness at injection site): 3 people, 17.65%
  6. Injection Site Nodule (small swelling or aggregation of cells in the body, esp. an abnormal one at injection site): 3 people, 17.65%
  7. Anovulatory Cycle (menstrual cycle during which the ovaries do not release an oocyte): 2 people, 11.76%
  8. Depression: 2 people, 11.76%
  9. Dizziness: 2 people, 11.76%
  10. Fainting (loss of consciousness and postural tone): 2 people, 11.76%

What are the existing conditions these people have? *

  1. Anaemia (lack of blood): 3 people, 17.65%
  2. The Flu (the flu is caused by an influenza virus): 1 person, 5.88%
  3. Sleep Disorder: 1 person, 5.88%
  4. Pain: 1 person, 5.88%
  5. Gastritis - Chronic (long lasting inflammation of stomach): 1 person, 5.88%
  6. Gastric Disorder (disease of stomach): 1 person, 5.88%
  7. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 5.88%
  8. Asthma: 1 person, 5.88%
  9. Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 5.88%
  10. Abdominal Pain: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Depo-provera and have Labyrinthitis?

- Check whether Labyrinthitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Depo-provera:

Labyrinthitis treatments and more:

How severe was Labyrinthitis and when was it recovered:

Expand to all the drugs that have ingredients of medroxyprogesterone acetate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Depo-provera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Labyrinthitis:

Browse all the conditions that are associated with Labyrinthitis:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on medroxyprogesterone acetate (the active ingredients of Depo-provera) and Depo-provera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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