Dexamethasone and Heart valve incompetence - a phase IV clinical study of FDA data

Summary:

Heart valve incompetence is reported as a side effect among people who take Dexamethasone (dexamethasone), especially for people who are female, 60+ old, also take Spironolactone, and have Pulmonary hypertension.

The phase IV clinical study analyzes which people have Heart valve incompetence when taking Dexamethasone. It is created by eHealthMe based on reports of 161,257 people who have side effects when taking Dexamethasone from the FDA, and is updated regularly.

What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.

What is Heart valve incompetence?

Heart valve incompetence (heart's valves do not work correctly) is found to be associated with 507 drugs and 503 conditions by eHealthMe. Check the latest studies of Heart valve incompetence.

On Jul, 12, 2026

161,257 people reported to have side effects when taking Dexamethasone.
Among them, 26 people (0.02%) have Heart valve incompetence.

Could Dexamethasone cause Heart valve incompetence?

Among these 26 people:

What is the gender of people who have Heart valve incompetence when taking Dexamethasone? *

female: 70.83 %
male: 29.17 %

What is the age of people who have Heart valve incompetence when taking Dexamethasone? *

What are other drugs people take besides Dexamethasone? *

What are other side effects people have besides Heart valve incompetence? *

Fatigue (feeling of tiredness): 13 people, 50.00%
Bronchopulmonary Dysplasia (chronic lung disorder in infants - enlargement of an organ or tissue by the proliferation of cells of an abnormal type): 9 people, 34.62%
Upper Respiratory Tract Infection: 9 people, 34.62%
Drug Ineffective: 9 people, 34.62%
Acidosis (build-up of carbon dioxide in the blood): 9 people, 34.62%
Paleness (unusual lightness of skin colour): 9 people, 34.62%
Pulmonary Hypertensive Crisis (increase in blood pressure in the lung artery-crisis): 9 people, 34.62%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 9 people, 34.62%
Swallowing Difficulty: 9 people, 34.62%
Fever: 8 people, 30.77%

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 9 people, 34.62%
Seasonal Allergy (allergic condition due to certain season): 4 people, 15.38%
Prostate Cancer: 4 people, 15.38%
Breast Cancer Metastatic: 4 people, 15.38%
High Blood Pressure: 2 people, 7.69%
Diarrhea: 2 people, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.69%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 7.69%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 7.69%
Irritable Bowel Syndrome: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Dexamethasone and have Heart valve incompetence?

- Check whether Heart valve incompetence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dexamethasone:

Dexamethasone (161,927 reports)

Browse all side effects of Dexamethasone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart valve incompetence:

Heart valve incompetence (507 drugs)

Browse all the conditions that are associated with Heart valve incompetence:

Heart valve incompetence (503 conditions)

Related publications that referenced our studies

Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on dexamethasone (the active ingredients of Dexamethasone) and Dexamethasone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.