Dexamethasone and Sphincter of oddi dysfunction - a phase IV clinical study of FDA data

Summary:

Sphincter of oddi dysfunction is reported as a side effect among people who take Dexamethasone (dexamethasone), especially for people who are male, 40-49 old, also take Furosemide, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Sphincter of oddi dysfunction when taking Dexamethasone. It is created by eHealthMe based on reports of 161,257 people who have side effects when taking Dexamethasone from the FDA, and is updated regularly.

What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.

What is Sphincter of oddi dysfunction?

Sphincter of oddi dysfunction (dysfunction of a muscular valve that controls the flow of digestive juices) is found to be associated with 80 drugs and 219 conditions by eHealthMe. Check the latest studies of Sphincter of oddi dysfunction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

161,257 people reported to have side effects when taking Dexamethasone.
Among them, 12 people (0.01%) have Sphincter of oddi dysfunction.

Could Dexamethasone cause Sphincter of oddi dysfunction?

Among these 12 people:

What is the gender of people who have Sphincter of oddi dysfunction when taking Dexamethasone? *

female: 18.18 %
male: 81.82 %

What is the age of people who have Sphincter of oddi dysfunction when taking Dexamethasone? *

What are other drugs people take besides Dexamethasone? *

Zopiclone: 10 people, 83.33%
Propofol: 10 people, 83.33%
Mepivacaine Hydrochloride: 10 people, 83.33%
Novalgin: 10 people, 83.33%
Omeprazole: 10 people, 83.33%
Pantoprazole: 10 people, 83.33%
Hydrochlorothiazide: 10 people, 83.33%
Heparin: 10 people, 83.33%
Piroxicam: 10 people, 83.33%
Furosemide: 10 people, 83.33%

What are other side effects people have besides Sphincter of oddi dysfunction? *

Middle Insomnia (difficulty returning to sleep after awakening either in the middle of the night): 10 people, 83.33%
Heart Disease: 10 people, 83.33%
Metabolic Syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease): 10 people, 83.33%
Memory Loss: 10 people, 83.33%
Colon Neoplasm (cancer from uncontrolled cell growth in the colon or rectum): 10 people, 83.33%
Left Ventricular Dysfunction: 10 people, 83.33%
Joint Pain: 10 people, 83.33%
Itching: 10 people, 83.33%
Insomnia (sleeplessness): 10 people, 83.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 10 people, 83.33%

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 83.33%
Cardiac Failure: 10 people, 83.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 10 people, 83.33%
Myocarditis (inflammation of heart muscle myocardium): 9 people, 75.00%
Congestive Cardiomyopathy (weakening of heart muscle): 9 people, 75.00%
Local Anaesthesia: 8 people, 66.67%
Anaesthesia: 8 people, 66.67%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 8.33%
Myelopathy (any neurologic deficit related to the spinal cord): 1 person, 8.33%
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Dexamethasone and have Sphincter of oddi dysfunction?

- Check whether Sphincter of oddi dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dexamethasone:

Dexamethasone (161,927 reports)

Browse all side effects of Dexamethasone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sphincter of oddi dysfunction:

Sphincter of oddi dysfunction (81 drugs)

Browse all the conditions that are associated with Sphincter of oddi dysfunction:

Sphincter of oddi dysfunction (219 conditions)

Related publications that referenced our studies

Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on dexamethasone (the active ingredients of Dexamethasone) and Dexamethasone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.