Diclofenac sodium and Ulcerative keratitis - a phase IV clinical study of FDA data

Summary:

Ulcerative keratitis is reported as a side effect among people who take Diclofenac sodium (diclofenac sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Ofloxacin, and have Glaucoma.

The phase IV clinical study analyzes which people have Ulcerative keratitis when taking Diclofenac sodium. It is created by eHealthMe based on reports of 41,731 people who have side effects when taking Diclofenac sodium from the FDA, and is updated regularly.

What is Diclofenac sodium?

Diclofenac sodium has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 43,018 Diclofenac sodium users. Check the latest studies of Diclofenac sodium.

What is Ulcerative keratitis?

Ulcerative keratitis (ulcerative inflammation of the cornea) is found to be associated with 295 drugs and 743 conditions by eHealthMe. Check the latest studies of Ulcerative keratitis.

On Jul, 20, 2026

41,731 people reported to have side effects when taking Diclofenac sodium.
Among them, 31 people (0.07%) have Ulcerative keratitis.

Could Diclofenac sodium cause Ulcerative keratitis?

Among these 31 people:

How long have people been on Diclofenac sodium when they have Ulcerative keratitis? *

What is the gender of people who have Ulcerative keratitis when taking Diclofenac sodium? *

female: 32.14 %
male: 67.86 %

What is the age of people who have Ulcerative keratitis when taking Diclofenac sodium? *

What are other drugs people take besides Diclofenac sodium? *

Ofloxacin: 8 people, 25.81%
Bimatoprost: 4 people, 12.90%
Ganciclovir: 4 people, 12.90%
Dexamethasone: 2 people, 6.45%
Zovirax: 1 person, 3.23%
Enbrel: 1 person, 3.23%
Besivance: 1 person, 3.23%
Betamethasone Dipropionate: 1 person, 3.23%
Betamethasone Sodium Phosphate: 1 person, 3.23%
Brimonidine: 1 person, 3.23%

What are other side effects people have besides Ulcerative keratitis? *

Corneal Thinning: 8 people, 25.81%
Eye Pain: 7 people, 22.58%
Corneal Opacity (scarring or clouding of the cornea): 7 people, 22.58%
Corneal Perforation (small hole in a cornea): 6 people, 19.35%
Conjunctival Hyperaemia (congestion of conjunctival vessels): 5 people, 16.13%
Vision Blurred: 5 people, 16.13%
Ciliary Hyperaemia (excessive accumulation of blood in a part of inside of eye tissue): 5 people, 16.13%
Meibomian Gland Dysfunction (dry eyes): 4 people, 12.90%
Corneal Oedema (corneal swelling): 4 people, 12.90%
Eye Inflammation: 4 people, 12.90%

What are the existing conditions these people have? *

Ocular Hyperaemia (an abnormally large amount of blood in eye): 5 people, 16.13%
Glaucoma (increased fluid pressure in the eye with vision loss): 5 people, 16.13%
Eye Irritation: 4 people, 12.90%
Dry Eyes (lack of adequate tears): 2 people, 6.45%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 3.23%
Mycotic Corneal Ulcer (ulcer of cornea due to fungal infection): 1 person, 3.23%
Keratoconus (a condition in which your eye's cornea is unable to hold its round shape): 1 person, 3.23%
Conjunctivitis (pink eye): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Diclofenac sodium and have Ulcerative keratitis?

- Check whether Ulcerative keratitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Diclofenac sodium:

Diclofenac sodium (43,018 reports)

Browse all side effects of Diclofenac sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ulcerative keratitis:

Ulcerative keratitis (295 drugs)

Browse all the conditions that are associated with Ulcerative keratitis:

Ulcerative keratitis (743 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium (the active ingredients of Diclofenac sodium) and Diclofenac sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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