Diflucan and Multiple sclerosis relapse - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis relapse is reported as a side effect among people who take Diflucan (fluconazole), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Ampyra, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Multiple sclerosis relapse when taking Diflucan. It is created by eHealthMe based on reports of 27,552 people who have side effects when taking Diflucan from the FDA, and is updated regularly.

What is Diflucan?

Diflucan has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 28,471 Diflucan users. Check the latest studies of Diflucan.

What is Multiple sclerosis relapse?

Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,032 drugs and 943 conditions by eHealthMe. Check the latest studies of Multiple sclerosis relapse.

On Jul, 04, 2026

27,552 people reported to have side effects when taking Diflucan.
Among them, 40 people (0.15%) have Multiple sclerosis relapse.

Could Diflucan cause Multiple sclerosis relapse?

Among these 40 people:

How long have people been on Diflucan when they have Multiple sclerosis relapse? *

What is the gender of people who have Multiple sclerosis relapse when taking Diflucan? *

female: 92.5 %
male: 7.5 %

What is the age of people who have Multiple sclerosis relapse when taking Diflucan? *

What are other drugs people take besides Diflucan? *

What are other side effects people have besides Multiple sclerosis relapse? *

Fatigue (feeling of tiredness): 18 people, 45.00%
Weakness: 14 people, 35.00%
Muscle Spasms (muscle contraction): 13 people, 32.50%
Pain: 9 people, 22.50%
Vision Blurred: 8 people, 20.00%
Hypoaesthesia (reduced sense of touch or sensation): 8 people, 20.00%
Urinary Tract Infection: 8 people, 20.00%
Fungal Infection: 7 people, 17.50%
Stress And Anxiety: 7 people, 17.50%
Dyspnea (difficult or laboured breathing): 6 people, 15.00%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 29 people, 72.50%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 9 people, 22.50%
Pain: 5 people, 12.50%
Gait Disturbance: 4 people, 10.00%
Urinary Tract Infection: 3 people, 7.50%
Fungal Infection: 3 people, 7.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 5.00%
Migraine (headache): 2 people, 5.00%
Stress And Anxiety: 2 people, 5.00%
Fatigue (feeling of tiredness): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Diflucan and have Multiple sclerosis relapse?

- Check whether Multiple sclerosis relapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Diflucan:

Diflucan (28,471 reports)

Browse all side effects of Diflucan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis relapse:

Multiple sclerosis relapse (1,032 drugs)

Browse all the conditions that are associated with Multiple sclerosis relapse:

Multiple sclerosis relapse (943 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluconazole (the active ingredients of Diflucan) and Diflucan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.