Divalproex and Stable angina - a phase IV clinical study of FDA data

Summary:

Stable angina is reported as a side effect among people who take Divalproex (divalproex sodium), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Methylphenidate Hydrochloride, and have Attention deficit hyperactivity disorder.

The phase IV clinical study analyzes which people have Stable angina when taking Divalproex. It is created by eHealthMe based on reports of 13,527 people who have side effects when taking Divalproex from the FDA, and is updated regularly.

What is Divalproex?

Divalproex has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 14,063 Divalproex users. Check the latest studies of Divalproex.

What is Stable angina?

Stable angina (a constant chest pain) is found to be associated with 1,620 drugs and 2,100 conditions by eHealthMe. Check the latest studies of Stable angina.



On Jul, 10, 2026

13,527 people reported to have side effects when taking Divalproex.
Among them, 16 people (0.12%) have Stable angina.

Could Divalproex cause Stable angina?

Among these 16 people:

How long have people been on Divalproex when they have Stable angina? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Stable angina when taking Divalproex? *

  • female: 41.67 %
  • male: 58.33 %

What is the age of people who have Stable angina when taking Divalproex? *

  • 0-1: 0.0 %
  • 2-9: 9.09 %
  • 10-19: 0.0 %
  • 20-29: 18.18 %
  • 30-39: 27.27 %
  • 40-49: 9.09 %
  • 50-59: 27.27 %
  • 60+: 9.09 %

What are other drugs people take besides Divalproex? *

  1. Inflectra: 3 people, 18.75%
  2. Atomoxetine: 3 people, 18.75%
  3. Methylphenidate Hydrochloride: 3 people, 18.75%
  4. Xanax: 2 people, 12.50%
  5. Vraylar: 2 people, 12.50%
  6. Yuflyma: 2 people, 12.50%
  7. Sertraline: 2 people, 12.50%
  8. Aspirin: 2 people, 12.50%
  9. Pantoprazole Sodium: 2 people, 12.50%
  10. Magnesium: 2 people, 12.50%

What are other side effects people have besides Stable angina? *

  1. Nausea (feeling of having an urge to vomit): 4 people, 25.00%
  2. Rashes (redness): 4 people, 25.00%
  3. Fistula (an abnormal connection or passageway between two): 3 people, 18.75%
  4. Depressive Symptom: 3 people, 18.75%
  5. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 3 people, 18.75%
  6. Headache (pain in head): 3 people, 18.75%
  7. Muscle Twitching: 3 people, 18.75%
  8. Heart Rate Increased: 3 people, 18.75%
  9. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 18.75%
  10. Diarrhea: 3 people, 18.75%

What are the existing conditions these people have? *

  1. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 4 people, 25.00%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 18.75%
  3. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 12.50%
  4. Sleep Disorder: 1 person, 6.25%
  5. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 6.25%
  6. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 6.25%
  7. Parkinson's Disease: 1 person, 6.25%
  8. Mood Swings (an extreme or rapid change in mood): 1 person, 6.25%
  9. High Blood Cholesterol: 1 person, 6.25%
  10. Hallucinations (sensations that appear real but are created by your mind): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Divalproex and have Stable angina?

- Check whether Stable angina is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Divalproex:

Stable angina treatments and more:

How severe was Stable angina and when was it recovered:

Expand to all the drugs that have ingredients of divalproex sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Divalproex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stable angina:

Browse all the conditions that are associated with Stable angina:


How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Divalproex) and Divalproex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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