Doxycycline and Bladder dysfunction - a phase IV clinical study of FDA data

Summary:

Bladder dysfunction is reported as a side effect among people who take Doxycycline (doxycycline hyclate), especially for people who are female, 50-59 old, also take Lasix, and have Fibromyalgia.

The phase IV clinical study analyzes which people have Bladder dysfunction when taking Doxycycline. It is created by eHealthMe based on reports of 57,458 people who have side effects when taking Doxycycline from the FDA, and is updated regularly.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,861 Doxycycline users. Check the latest studies of Doxycycline.

What is Bladder dysfunction?

Bladder dysfunction is found to be associated with 253 drugs and 272 conditions by eHealthMe. Check the latest studies of Bladder dysfunction.

On Jan, 26, 2026

57,458 people reported to have side effects when taking Doxycycline.
Among them, 11 people (0.02%) have Bladder dysfunction.

Could Doxycycline cause Bladder dysfunction?

Among these 11 people:

What is the gender of people who have Bladder dysfunction when taking Doxycycline? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Bladder dysfunction when taking Doxycycline? *

What are other drugs people take besides Doxycycline? *

What are other side effects people have besides Bladder dysfunction? *

Nausea (feeling of having an urge to vomit): 10 people, 90.91%
Stress And Anxiety: 10 people, 90.91%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 10 people, 90.91%
Joint Pain: 10 people, 90.91%
Pain: 10 people, 90.91%
Gait Disturbance: 10 people, 90.91%
Erection Problems: 9 people, 81.82%
Osteonecrosis Of Jaw (death of bone of jaw): 9 people, 81.82%
Oedema Peripheral (superficial swelling): 9 people, 81.82%
Neck Pain: 9 people, 81.82%

What are the existing conditions these people have? *

Breast Cancer: 8 people, 72.73%
Fibromyalgia (a long-term condition which causes pain all over the body): 8 people, 72.73%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 7 people, 63.64%
Neuropathy Peripheral (surface nerve damage): 7 people, 63.64%
Stress And Anxiety: 2 people, 18.18%
Osteoporosis (bones weak and more likely to break): 1 person, 9.09%
Constipation: 1 person, 9.09%
Back Disorder: 1 person, 9.09%
Back Pain: 1 person, 9.09%
Blood Glucose Increased: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Doxycycline and have Bladder dysfunction?

- Check whether Bladder dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Doxycycline:

Doxycycline (60,861 reports)

Browse all side effects of Doxycycline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder dysfunction:

Bladder dysfunction (253 drugs)

Browse all the conditions that are associated with Bladder dysfunction:

Bladder dysfunction (272 conditions)

Drugs similar to Doxycycline and Bladder dysfunction :

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate (the active ingredients of Doxycycline) and Doxycycline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.