Dulcolax and Fluid overload - a phase IV clinical study of FDA data

Summary:

Fluid overload is reported as a side effect among people who take Dulcolax (bisacodyl), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Heparin, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Fluid overload when taking Dulcolax. It is created by eHealthMe based on reports of 12,769 people who have side effects when taking Dulcolax from the FDA, and is updated regularly.

What is Dulcolax?

Dulcolax has active ingredients of bisacodyl. It is often used in constipation. eHealthMe is studying from 12,897 Dulcolax users. Check the latest studies of Dulcolax.

What is Fluid overload?

Fluid overload (too much fluid in the blood) is found to be associated with 1,023 drugs and 1,051 conditions by eHealthMe. Check the latest studies of Fluid overload.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

12,769 people reported to have side effects when taking Dulcolax.
Among them, 30 people (0.23%) have Fluid overload.

Could Dulcolax cause Fluid overload?

Among these 30 people:

How long have people been on Dulcolax when they have Fluid overload? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Fluid overload when taking Dulcolax? *

  • female: 63.33 %
  • male: 36.67 %

What is the age of people who have Fluid overload when taking Dulcolax? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.7 %
  • 40-49: 11.11 %
  • 50-59: 37.04 %
  • 60+: 48.15 %

What are other drugs people take besides Dulcolax? *

  1. Heparin: 12 people, 40.00%
  2. Percocet: 9 people, 30.00%
  3. Coumadin: 8 people, 26.67%
  4. Pepcid: 8 people, 26.67%
  5. Tylenol: 8 people, 26.67%
  6. Protonix: 7 people, 23.33%
  7. Lovenox: 7 people, 23.33%
  8. Lasix: 7 people, 23.33%
  9. Prilosec: 7 people, 23.33%
  10. Dilaudid: 7 people, 23.33%

What are other side effects people have besides Fluid overload? *

  1. Cardiac Failure Congestive: 10 people, 33.33%
  2. Hypotension (abnormally low blood pressure): 9 people, 30.00%
  3. Dyspnea (difficult or laboured breathing): 8 people, 26.67%
  4. Fatigue (feeling of tiredness): 7 people, 23.33%
  5. Oedema Peripheral (superficial swelling): 7 people, 23.33%
  6. Nausea (feeling of having an urge to vomit): 7 people, 23.33%
  7. Nausea And Vomiting: 6 people, 20.00%
  8. Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 6 people, 20.00%
  9. Chest Pain: 5 people, 16.67%
  10. Dizziness: 5 people, 16.67%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 5 people, 16.67%
  2. Back Pain: 4 people, 13.33%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 13.33%
  4. Pain: 4 people, 13.33%
  5. Hypotension (abnormally low blood pressure): 4 people, 13.33%
  6. Sleep Disorder: 3 people, 10.00%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 10.00%
  8. Blood Glucose Increased: 3 people, 10.00%
  9. Cardiac Disorder: 3 people, 10.00%
  10. Dehydration (dryness resulting from the removal of water): 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Dulcolax and have Fluid overload?

- Check whether Fluid overload is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Dulcolax:

Fluid overload treatments and more:

How severe was Fluid overload and when was it recovered:

Expand to all the drugs that have ingredients of bisacodyl:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dulcolax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fluid overload:

Browse all the conditions that are associated with Fluid overload:


How the study uses the data?

The study uses data from the FDA. It is based on bisacodyl (the active ingredients of Dulcolax) and Dulcolax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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