Eligard and Cachexia - a phase IV clinical study of FDA data

Summary:

Cachexia is reported as a side effect among people who take Eligard (leuprolide acetate), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Casodex, and have Prostatic specific antigen increased.

The phase IV clinical study analyzes which people have Cachexia when taking Eligard. It is created by eHealthMe based on reports of 44,585 people who have side effects when taking Eligard from the FDA, and is updated regularly.

What is Eligard?

Eligard has active ingredients of leuprolide acetate. It is often used in prostate cancer. eHealthMe is studying from 44,652 Eligard users. Check the latest studies of Eligard.

What is Cachexia?

Cachexia (loss of weight) is found to be associated with 706 drugs and 1,197 conditions by eHealthMe. Check the latest studies of Cachexia.



On Dec, 14, 2025

44,585 people reported to have side effects when taking Eligard.
Among them, 17 people (0.04%) have Cachexia.

Could Eligard cause Cachexia?

Among these 17 people:

How long have people been on Eligard when they have Cachexia? *

  • < 1 month: 25 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 25 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Cachexia when taking Eligard? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Cachexia when taking Eligard? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Eligard? *

  1. Xtandi: 2 people, 11.76%
  2. Casodex: 2 people, 11.76%
  3. Morphine Sulfate: 1 person, 5.88%
  4. Docetaxel: 1 person, 5.88%

What are other side effects people have besides Cachexia? *

  1. Weakness: 10 people, 58.82%
  2. Fatigue (feeling of tiredness): 7 people, 41.18%
  3. Weight Decreased: 6 people, 35.29%
  4. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 35.29%
  5. Dyspnea (difficult or laboured breathing): 5 people, 29.41%
  6. Hot Flush (sudden feelings of heat): 5 people, 29.41%
  7. Injection Site Mass: 4 people, 23.53%
  8. Injection Site Pain: 4 people, 23.53%
  9. Dizziness: 3 people, 17.65%
  10. Nausea (feeling of having an urge to vomit): 3 people, 17.65%

What are the existing conditions these people have? *

  1. Prostatic Specific Antigen Increased: 2 people, 11.76%
  2. Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 5.88%
  3. Metastases To Bone (cancer spreads to bone): 1 person, 5.88%
  4. Bone Disorder: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Eligard and have Cachexia?

- Check whether Cachexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eligard:

Cachexia treatments and more:

How severe was Cachexia and when was it recovered:

Expand to all the drugs that have ingredients of leuprolide acetate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Eligard:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cachexia:

Browse all the conditions that are associated with Cachexia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on leuprolide acetate (the active ingredients of Eligard) and Eligard (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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