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Eligard and Cataract - a phase IV clinical study of FDA data

Summary:

Cataract is reported as a side effect among people who take Eligard (leuprolide acetate), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Casodex, and have Metastases to bone.

The phase IV clinical study analyzes which people have Cataract when taking Eligard. It is created by eHealthMe based on reports of 44,585 people who have side effects when taking Eligard from the FDA, and is updated regularly.

What is Eligard?

Eligard has active ingredients of leuprolide acetate. It is often used in prostate cancer. eHealthMe is studying from 44,652 Eligard users. Check the latest studies of Eligard.

What is Cataract?

Cataract (clouding of the lens inside the eye) is found to be associated with 1,894 drugs and 2,131 conditions by eHealthMe. Check the latest studies of Cataract.

On Jul, 27, 2026

44,585 people reported to have side effects when taking Eligard.
Among them, 93 people (0.21%) have Cataract.

Could Eligard cause Cataract?

Among these 93 people:

How long have people been on Eligard when they have Cataract? *

  • < 1 month: 20 %
  • 1 - 6 months: 40 %
  • 6 - 12 months: 20 %
  • 1 - 2 years: 20 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Cataract when taking Eligard? *

  • female: 2.2 %
  • male: 97.8 %

What is the age of people who have Cataract when taking Eligard? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 2 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 98 %

What are other drugs people take besides Eligard? *

  1. Lupron: 29 people, 31.18%
  2. Casodex: 29 people, 31.18%
  3. Zometa: 28 people, 30.11%
  4. Remeron: 25 people, 26.88%
  5. Ultram: 23 people, 24.73%
  6. Protonix: 16 people, 17.20%
  7. Compazine: 15 people, 16.13%
  8. Reglan: 15 people, 16.13%
  9. Restoril: 15 people, 16.13%
  10. Peridex: 15 people, 16.13%

What are other side effects people have besides Cataract? *

  1. Weakness: 42 people, 45.16%
  2. Fatigue (feeling of tiredness): 35 people, 37.63%
  3. Weight Decreased: 33 people, 35.48%
  4. Dizziness: 32 people, 34.41%
  5. Stress And Anxiety: 32 people, 34.41%
  6. Fall: 31 people, 33.33%
  7. Confusional State: 29 people, 31.18%
  8. Pain: 29 people, 31.18%
  9. Hearing Loss: 28 people, 30.11%
  10. Metastases To Bone (cancer spreads to bone): 28 people, 30.11%

What are the existing conditions these people have? *

  1. Toothaches (tooth pain): 13 people, 13.98%
  2. Metastases To Bone (cancer spreads to bone): 13 people, 13.98%
  3. Muscle Spasms (muscle contraction): 11 people, 11.83%
  4. Depression: 4 people, 4.30%
  5. Bone Neoplasm Malignant (cancer of bone): 3 people, 3.23%
  6. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 1 person, 1.08%
  7. Prostate Cancer Metastatic: 1 person, 1.08%
  8. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 1 person, 1.08%
  9. Infection: 1 person, 1.08%
  10. High Blood Pressure: 1 person, 1.08%

* Approximation only. Some reports may have incomplete information.

Do you take Eligard and have Cataract?

- Check whether Cataract is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eligard:

Cataract treatments and more:

How severe was Cataract and when was it recovered:

Expand to all the drugs that have ingredients of leuprolide acetate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Eligard:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cataract:

Browse all the conditions that are associated with Cataract:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on leuprolide acetate (the active ingredients of Eligard) and Eligard (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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