Eliquis and Prothrombin time shortened - a phase IV clinical study of FDA data

Summary:

Prothrombin time shortened is reported as a side effect among people who take Eliquis (apixaban), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Paracetamol, and have Cardiac failure.

The phase IV clinical study analyzes which people have Prothrombin time shortened when taking Eliquis. It is created by eHealthMe based on reports of 189,425 people who have side effects when taking Eliquis from the FDA, and is updated regularly.

What is Eliquis?

Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 191,864 Eliquis users. Check the latest studies of Eliquis.

What is Prothrombin time shortened?

Prothrombin time shortened is found to be associated with 236 drugs and 536 conditions by eHealthMe. Check the latest studies of Prothrombin time shortened.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

189,425 people reported to have side effects when taking Eliquis.
Among them, 26 people (0.01%) have Prothrombin time shortened.

Could Eliquis cause Prothrombin time shortened?

Among these 26 people:

How long have people been on Eliquis when they have Prothrombin time shortened? *

What is the gender of people who have Prothrombin time shortened when taking Eliquis? *

female: 57.14 %
male: 42.86 %

What is the age of people who have Prothrombin time shortened when taking Eliquis? *

What are other drugs people take besides Eliquis? *

What are other side effects people have besides Prothrombin time shortened? *

Hepatocellular Injury (liver injury): 7 people, 26.92%
Haematocrit Decreased: 5 people, 19.23%
Renal Impairment (severely reduced kidney function): 5 people, 19.23%
Hypotension (abnormally low blood pressure): 4 people, 15.38%
Red Blood Cell Count Decreased: 4 people, 15.38%
Blood Creatinine Increased: 4 people, 15.38%
White Blood Cell Count Increased: 3 people, 11.54%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 3 people, 11.54%
Haemoglobin Decreased: 3 people, 11.54%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 11.54%

What are the existing conditions these people have? *

Cardiac Failure: 9 people, 34.62%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 8 people, 30.77%
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 6 people, 23.08%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 6 people, 23.08%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 3 people, 11.54%
Pulmonary Vascular Disorder: 3 people, 11.54%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 11.54%
High Blood Pressure: 3 people, 11.54%
Acute Kidney Failure: 3 people, 11.54%
Parkinson's Disease: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Eliquis and have Prothrombin time shortened?

- Check whether Prothrombin time shortened is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eliquis:

Eliquis (191,864 reports)

Browse all side effects of Eliquis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Prothrombin time shortened:

Prothrombin time shortened (236 drugs)

Browse all the conditions that are associated with Prothrombin time shortened:

Prothrombin time shortened (536 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on apixaban (the active ingredients of Eliquis) and Eliquis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.