Enbrel and Keloids - a phase IV clinical study of FDA data


Keloids is found among people who take Enbrel, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years.

The phase IV clinical study analyzes which people take Enbrel and have Keloids. It is created by eHealthMe based on reports of 633,316 people who have side effects when taking Enbrel from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 19, 2022

633,316 people reported to have side effects when taking Enbrel.
Among them, 21 people (0.0%) have Keloids.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 635,034 Enbrel users for its effectiveness, alternative drugs and more.

What is Keloids?

Keloids (overgrown scars left from skin injuries) is found to be associated with 626 drugs and 441 conditions by eHealthMe.

Number of Enbrel and Keloids reports submitted per year:

Could Enbrel cause Keloids?

Time on Enbrel when people have Keloids *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 25 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 25 %
  • 5 - 10 years: 50 %
  • 10+ years: 0.0 %

Gender of people who have Keloids when taking Enbrel *:

  • female: 57.14 %
  • male: 42.86 %

Age of people who have Keloids when taking Enbrel *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 33.33 %
  • 30-39: 11.11 %
  • 40-49: 11.11 %
  • 50-59: 0.0 %
  • 60+: 44.44 %

Common drugs people take besides Enbrel *:

  1. Hydrocodone Bitartrate And Acetaminophen: 7 people, 33.33%
  2. Xyrem: 7 people, 33.33%
  3. Vitamin D3: 7 people, 33.33%
  4. Vicodin: 7 people, 33.33%
  5. Maxalt: 7 people, 33.33%
  6. Dramamine: 7 people, 33.33%
  7. Hydrocodone: 7 people, 33.33%
  8. Nuvigil: 7 people, 33.33%
  9. Humira: 2 people, 9.52%
  10. Zovirax: 2 people, 9.52%

Common side effects people have besides Keloids *:

  1. Stress And Anxiety: 9 people, 42.86%
  2. Nausea And Vomiting: 9 people, 42.86%
  3. Indigestion: 8 people, 38.10%
  4. Vitamin D Decreased: 7 people, 33.33%
  5. Vascular Compression: 7 people, 33.33%
  6. Abdominal Pain Upper: 7 people, 33.33%
  7. Depressed Mood: 7 people, 33.33%
  8. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 33.33%
  9. Intervertebral Disc Protrusion (spinal disc protrusion): 6 people, 28.57%
  10. Hepatic Mass: 5 people, 23.81%

Common conditions people have *:

  1. Nausea And Vomiting: 7 people, 33.33%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 33.33%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 33.33%
  4. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 23.81%
  5. Psoriasis (immune-mediated disease that affects the skin): 2 people, 9.52%
  6. Oropharyngeal Pain: 2 people, 9.52%
  7. Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 2 people, 9.52%
  8. Adenoiditis (inflammation of an abnormally enlarged mass of lymphoid tissue at the back of the pharynx): 2 people, 9.52%
  9. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 4.76%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Enbrel and have Keloids?

Check whether Keloids is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Keloids and when was it recovered:

Expand to all the drugs that have ingredients of etanercept:

Alternative drugs to, pros and cons of Enbrel:

Common Enbrel side effects:

Browse all side effects of Enbrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Keloids treatments and more:

COVID vaccines that are related to Keloids:

All the drugs that are associated with Keloids:

All the conditions that are associated with Keloids:

How the study uses the data?

The study uses data from the FDA. It is based on etanercept (the active ingredients of Enbrel) and Enbrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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