Enhertu and Weight decreased - a phase IV clinical study of FDA data

Summary:

Weight decreased is reported as a side effect among people who take Enhertu (fam-trastuzumab deruxtecan-nxki), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Decadron, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Weight decreased when taking Enhertu. It is created by eHealthMe based on reports of 5,111 people who have side effects when taking Enhertu from the FDA, and is updated regularly.

What is Enhertu?

Enhertu has active ingredients of fam-trastuzumab deruxtecan-nxki. eHealthMe is studying from 5,113 Enhertu users. Check the latest studies of Enhertu.

What is Weight decreased?

Weight decreased is found to be associated with 3,385 drugs and 4,752 conditions by eHealthMe. Check the latest studies of Weight decreased.

On Jul, 29, 2026

5,111 people reported to have side effects when taking Enhertu.
Among them, 132 people (2.58%) have Weight decreased.

Among these 132 people:

* Approximation only. Some reports may have incomplete information.

Do you take Enhertu and have Weight decreased?

- Check whether Weight decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Enhertu:

Enhertu (5,113 reports)

Weight decreased treatments and more:

Weight decreased (364,522 reports)

How severe was Weight decreased and when was it recovered:

Weight decreased in Enhertu

Expand to all the drugs that have ingredients of fam-trastuzumab deruxtecan-nxki:

Weight decreased and drugs with ingredients of fam-trastuzumab deruxtecan-nxki

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Enhertu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight decreased:

Weight decreased (3,385 drugs)

Browse all the conditions that are associated with Weight decreased:

Weight decreased (4,752 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fam-trastuzumab deruxtecan-nxki (the active ingredients of Enhertu) and Enhertu (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.