Epivir and Rickets - a phase IV clinical study of FDA data

Summary:

Rickets is reported as a side effect among people who take Epivir (lamivudine), especially for people who are male, 50-59 old, have been taking the drug for 2 - 5 years also take Norvir, and have High blood pressure.

The phase IV clinical study analyzes which people have Rickets when taking Epivir. It is created by eHealthMe based on reports of 16,823 people who have side effects when taking Epivir from the FDA, and is updated regularly.

What is Epivir?

Epivir has active ingredients of lamivudine. It is often used in hiv infection. eHealthMe is studying from 16,870 Epivir users. Check the latest studies of Epivir.

What is Rickets?

Rickets (softening of bones) is found to be associated with 1,092 drugs and 1,457 conditions by eHealthMe. Check the latest studies of Rickets.



On Jul, 09, 2026

16,823 people reported to have side effects when taking Epivir.
Among them, 48 people (0.29%) have Rickets.

Could Epivir cause Rickets?

Among these 48 people:

How long have people been on Epivir when they have Rickets? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Rickets when taking Epivir? *

  • female: 35.42 %
  • male: 64.58 %

What is the age of people who have Rickets when taking Epivir? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.7 %
  • 20-29: 0.0 %
  • 30-39: 16.22 %
  • 40-49: 40.54 %
  • 50-59: 40.54 %
  • 60+: 0.0 %

What are other drugs people take besides Epivir? *

  1. Norvir: 29 people, 60.42%
  2. Truvada: 25 people, 52.08%
  3. Ziagen: 21 people, 43.75%
  4. Atripla: 20 people, 41.67%
  5. Tivicay: 20 people, 41.67%
  6. Viread: 19 people, 39.58%
  7. Retrovir: 17 people, 35.42%
  8. Sustiva: 16 people, 33.33%
  9. Kaletra: 16 people, 33.33%
  10. Isentress: 16 people, 33.33%

What are other side effects people have besides Rickets? *

  1. Emotional Distress: 35 people, 72.92%
  2. Pain: 35 people, 72.92%
  3. Stress And Anxiety: 35 people, 72.92%
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 31 people, 64.58%
  5. Osteoporosis (bones weak and more likely to break): 24 people, 50.00%
  6. Chronic Kidney Disease: 22 people, 45.83%
  7. Blood Creatinine Increased: 19 people, 39.58%
  8. Acute Kidney Failure: 16 people, 33.33%
  9. Bone Density Decreased: 16 people, 33.33%
  10. Depression: 16 people, 33.33%

What are the existing conditions these people have? *

  1. High Blood Pressure: 6 people, 12.50%
  2. Anaemia (lack of blood): 3 people, 6.25%
  3. Osteoporosis (bones weak and more likely to break): 3 people, 6.25%
  4. Inflammation: 3 people, 6.25%
  5. Transplant Rejection (a transplant material is not worked): 2 people, 4.17%
  6. Stable Angina (a constant chest pain): 2 people, 4.17%
  7. Renal Impairment (severely reduced kidney function): 2 people, 4.17%
  8. Hepatitis B: 2 people, 4.17%
  9. Nephropathy (damage to or disease of a kidney): 2 people, 4.17%
  10. Calcium Deficiency (lack of calcium): 1 person, 2.08%

* Approximation only. Some reports may have incomplete information.

Do you take Epivir and have Rickets?

- Check whether Rickets is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Epivir:

Rickets treatments and more:

How severe was Rickets and when was it recovered:

Expand to all the drugs that have ingredients of lamivudine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Epivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rickets:

Browse all the conditions that are associated with Rickets:


How the study uses the data?

The study uses data from the FDA. It is based on lamivudine (the active ingredients of Epivir) and Epivir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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