Estradiol and Acne aggravated - a phase IV clinical study of FDA data

Summary:

Acne aggravated is reported as a side effect among people who take Estradiol (estradiol), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Calcium, and have Crohn's disease.

The phase IV clinical study analyzes which people have Acne aggravated when taking Estradiol. It is created by eHealthMe based on reports of 17,352 people who have side effects when taking Estradiol from the FDA, and is updated regularly.

What is Estradiol?

Estradiol has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 18,986 Estradiol users. Check the latest studies of Estradiol.

What is Acne aggravated?

Acne aggravated (acne - a skin disease) is found to be associated with 1,230 drugs and 527 conditions by eHealthMe. Check the latest studies of Acne aggravated.

On Jul, 19, 2026

17,352 people reported to have side effects when taking Estradiol.
Among them, 48 people (0.28%) have Acne aggravated.

Among these 48 people:

How long have people been on Estradiol when they have Acne aggravated? *

What is the gender of people who have Acne aggravated when taking Estradiol? *

female: 100 %
male: 0.0 %

What is the age of people who have Acne aggravated when taking Estradiol? *

What are other drugs people take besides Estradiol? *

What are other side effects people have besides Acne aggravated? *

Fatigue (feeling of tiredness): 18 people, 37.50%
Joint Pain: 16 people, 33.33%
Itching: 12 people, 25.00%
Rashes (redness): 11 people, 22.92%
Drowsiness: 10 people, 20.83%
Urticaria (rash of round, red welts on the skin that itch intensely): 10 people, 20.83%
Headache (pain in head): 9 people, 18.75%
Back Pain: 8 people, 16.67%
Cough: 8 people, 16.67%
Dyspnea (difficult or laboured breathing): 8 people, 16.67%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 10 people, 20.83%
High Blood Pressure: 9 people, 18.75%
Asthma: 7 people, 14.58%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 12.50%
Migraine (headache): 6 people, 12.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 10.42%
High Blood Cholesterol: 4 people, 8.33%
Birth Control: 4 people, 8.33%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 4 people, 8.33%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Estradiol and have Acne aggravated?

- Check whether Acne aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Estradiol:

Estradiol (18,986 reports)

Browse all side effects of Estradiol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acne aggravated:

Acne aggravated (1,230 drugs)

Browse all the conditions that are associated with Acne aggravated:

Acne aggravated (527 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Estradiol) and Estradiol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.