Estradiol and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Estradiol (estradiol), especially for people who are female, 60+ old, also take Progesterone, and have Growth hormone deficiency.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Estradiol. It is created by eHealthMe based on reports of 17,352 people who have side effects when taking Estradiol from the FDA, and is updated regularly.

What is Estradiol?

Estradiol has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 18,978 Estradiol users. Check the latest studies of Estradiol.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,032 drugs and 1,426 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.

On Jan, 30, 2026

17,352 people reported to have side effects when taking Estradiol.
Among them, 36 people (0.21%) have Hyperthyroidism.

Among these 36 people:

What is the gender of people who have Hyperthyroidism when taking Estradiol? *

female: 100 %
male: 0.0 %

What is the age of people who have Hyperthyroidism when taking Estradiol? *

What are other drugs people take besides Estradiol? *

What are other side effects people have besides Hyperthyroidism? *

Insomnia (sleeplessness): 12 people, 33.33%
Hair Loss: 10 people, 27.78%
Malaise (a feeling of general discomfort or uneasiness): 10 people, 27.78%
Drug Intolerance (drug sensitivity): 7 people, 19.44%
Nail Bed Disorder (disease of nail bed): 6 people, 16.67%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 16.67%
Heart Rate Increased: 6 people, 16.67%
Fatigue (feeling of tiredness): 5 people, 13.89%
Osteoporosis (bones weak and more likely to break): 5 people, 13.89%
Itching: 5 people, 13.89%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 16.67%
Vasculitis (inflammation of a blood vessel or blood vessels): 6 people, 16.67%
High Blood Cholesterol: 6 people, 16.67%
Growth Hormone Deficiency: 6 people, 16.67%
High Blood Pressure: 5 people, 13.89%
Stable Angina (a constant chest pain): 4 people, 11.11%
Seasonal Allergy (allergic condition due to certain season): 4 people, 11.11%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 4 people, 11.11%
Diabetes: 4 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Estradiol and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Estradiol:

Estradiol (18,978 reports)

Hyperthyroidism treatments and more:

Hyperthyroidism (26,829 reports)

Browse all side effects of Estradiol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Hyperthyroidism (1,032 drugs)

Browse all the conditions that are associated with Hyperthyroidism:

Hyperthyroidism (1,426 conditions)

Drugs similar to Estradiol and Hyperthyroidism :

Related publications that referenced our studies

Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .
Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Estradiol) and Estradiol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.