Estradiol and Pancreatitis - a phase IV clinical study of FDA data

Summary:

Pancreatitis is reported as a side effect among people who take Estradiol (estradiol), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Aspirin, and have Narcolepsy.

The phase IV clinical study analyzes which people have Pancreatitis when taking Estradiol. It is created by eHealthMe based on reports of 17,352 people who have side effects when taking Estradiol from the FDA, and is updated regularly.

What is Estradiol?

Estradiol has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 18,986 Estradiol users. Check the latest studies of Estradiol.

What is Pancreatitis?

Pancreatitis (inflammation of pancreas) is found to be associated with 1,762 drugs and 2,027 conditions by eHealthMe. Check the latest studies of Pancreatitis.



On Aug, 11, 2026

17,352 people reported to have side effects when taking Estradiol.
Among them, 51 people (0.29%) have Pancreatitis.

Could Estradiol cause Pancreatitis?

Among these 51 people:

How long have people been on Estradiol when they have Pancreatitis? *

  • < 1 month: 40 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 40 %
  • 2 - 5 years: 20 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pancreatitis when taking Estradiol? *

  • female: 97.96 %
  • male: 2.04 %

What is the age of people who have Pancreatitis when taking Estradiol? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 10.34 %
  • 20-29: 3.45 %
  • 30-39: 3.45 %
  • 40-49: 20.69 %
  • 50-59: 31.03 %
  • 60+: 31.03 %

What are other drugs people take besides Estradiol? *

  1. Aspirin: 12 people, 23.53%
  2. Folic Acid: 10 people, 19.61%
  3. Risperdal: 8 people, 15.69%
  4. Zyprexa: 8 people, 15.69%
  5. Ibuprofen: 8 people, 15.69%
  6. Omeprazole: 8 people, 15.69%
  7. Atenolol: 8 people, 15.69%
  8. Depakote: 8 people, 15.69%
  9. Vitamin D3: 7 people, 13.73%
  10. Topamax: 7 people, 13.73%

What are other side effects people have besides Pancreatitis? *

  1. High Blood Pressure: 8 people, 15.69%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 15.69%
  3. Homicidal Ideation (thoughts about human killing another human): 5 people, 9.80%
  4. Diarrhea: 5 people, 9.80%
  5. Anaemia (lack of blood): 5 people, 9.80%
  6. Suicidal Ideation: 5 people, 9.80%
  7. Nausea (feeling of having an urge to vomit): 5 people, 9.80%
  8. Drug Intolerance (drug sensitivity): 5 people, 9.80%
  9. Self Injurious Behavior: 5 people, 9.80%
  10. High Blood Cholesterol: 4 people, 7.84%

What are the existing conditions these people have? *

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 6 people, 11.76%
  2. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 11.76%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 11.76%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 9.80%
  5. Drowsiness: 5 people, 9.80%
  6. High Blood Pressure: 4 people, 7.84%
  7. Neurofibroma (non-cancerous tumours that grow on nerves throughout the body): 3 people, 5.88%
  8. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 3 people, 5.88%
  9. Glioma (a type of tumour that starts in the brain or spine): 3 people, 5.88%
  10. Diabetes Insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Estradiol and have Pancreatitis?

- Check whether Pancreatitis is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Estradiol:

Pancreatitis treatments and more:

How severe was Pancreatitis and when was it recovered:

Expand to all the drugs that have ingredients of estradiol:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Estradiol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pancreatitis:

Browse all the conditions that are associated with Pancreatitis:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Estradiol) and Estradiol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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