Exidine and Agitation aggravated - a phase IV clinical study of FDA data

Summary:

Agitation aggravated is reported as a side effect among people who take Exidine (chlorhexidine gluconate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Osteoporosis.

The phase IV clinical study analyzes which people have Agitation aggravated when taking Exidine. It is created by eHealthMe based on reports of 17,245 people who have side effects when taking Exidine from the FDA, and is updated regularly.

What is Exidine?

Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.

What is Agitation aggravated?

Agitation aggravated (clinical depression in which the person exhibits irritability and restlessness) is found to be associated with 2,029 drugs and 914 conditions by eHealthMe. Check the latest studies of Agitation aggravated.



On Jul, 21, 2026

17,245 people reported to have side effects when taking Exidine.
Among them, 81 people (0.47%) have Agitation aggravated.

Could Exidine cause Agitation aggravated?

Among these 81 people:

How long have people been on Exidine when they have Agitation aggravated? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Agitation aggravated when taking Exidine? *

  • female: 62.34 %
  • male: 37.66 %

What is the age of people who have Agitation aggravated when taking Exidine? *

  • 0-1: 0.0 %
  • 2-9: 3.51 %
  • 10-19: 5.26 %
  • 20-29: 5.26 %
  • 30-39: 3.51 %
  • 40-49: 31.58 %
  • 50-59: 8.77 %
  • 60+: 42.11 %

What are other drugs people take besides Exidine? *

  1. Zometa: 35 people, 43.21%
  2. Benadryl: 25 people, 30.86%
  3. Zofran: 22 people, 27.16%
  4. Reglan: 22 people, 27.16%
  5. Prevacid: 19 people, 23.46%
  6. Amoxicillin: 19 people, 23.46%
  7. Diazepam: 18 people, 22.22%
  8. Norco: 18 people, 22.22%
  9. Zantac: 18 people, 22.22%
  10. Adapalene: 17 people, 20.99%

What are other side effects people have besides Agitation aggravated? *

  1. Pain: 40 people, 49.38%
  2. Dyspnea (difficult or laboured breathing): 38 people, 46.91%
  3. Stress And Anxiety: 37 people, 45.68%
  4. Injury: 33 people, 40.74%
  5. Weight Decreased: 31 people, 38.27%
  6. Osteonecrosis Of Jaw (death of bone of jaw): 28 people, 34.57%
  7. Insomnia (sleeplessness): 28 people, 34.57%
  8. Impaired Gastric Emptying: 28 people, 34.57%
  9. Hypoaesthesia (reduced sense of touch or sensation): 28 people, 34.57%
  10. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 28 people, 34.57%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 16 people, 19.75%
  2. Pain: 6 people, 7.41%
  3. Multiple Myeloma (cancer of the plasma cells): 6 people, 7.41%
  4. Metastases To Bone (cancer spreads to bone): 5 people, 6.17%
  5. Parkinson's Disease: 4 people, 4.94%
  6. Psychotic Disorder: 3 people, 3.70%
  7. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 2.47%
  8. Delusion (a false belief or opinion): 2 people, 2.47%
  9. Fever: 2 people, 2.47%
  10. Cardiac Failure: 2 people, 2.47%

* Approximation only. Some reports may have incomplete information.

Do you take Exidine and have Agitation aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exidine:

Agitation aggravated treatments and more:

How severe was Agitation aggravated and when was it recovered:

Expand to all the drugs that have ingredients of chlorhexidine gluconate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Agitation aggravated:

Browse all the conditions that are associated with Agitation aggravated:


How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Exidine) and Exidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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