Febuxostat and Rickets - a phase IV clinical study of FDA data

Summary:

Rickets is reported as a side effect among people who take Febuxostat (febuxostat), especially for people who are male, 60+ old, also take Vitamin B12, and have High blood pressure.

The phase IV clinical study analyzes which people have Rickets when taking Febuxostat. It is created by eHealthMe based on reports of 9,653 people who have side effects when taking Febuxostat from the FDA, and is updated regularly.

What is Febuxostat?

Febuxostat has active ingredients of febuxostat. eHealthMe is studying from 9,693 Febuxostat users. Check the latest studies of Febuxostat.

What is Rickets?

Rickets (softening of bones) is found to be associated with 1,086 drugs and 1,459 conditions by eHealthMe. Check the latest studies of Rickets.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

9,653 people reported to have side effects when taking Febuxostat.
Among them, 12 people (0.12%) have Rickets.

Among these 12 people:

What is the gender of people who have Rickets when taking Febuxostat? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Rickets when taking Febuxostat? *

What are other drugs people take besides Febuxostat? *

Albuterol: 5 people, 41.67%
Vitamin B12: 5 people, 41.67%
Daptomycin: 4 people, 33.33%
Kayexalate: 4 people, 33.33%
Percocet: 4 people, 33.33%
Paroxetine Hydrochloride: 4 people, 33.33%
Paroxetine: 4 people, 33.33%
Pantoprazole: 4 people, 33.33%
Opsumit: 4 people, 33.33%
Ondansetron: 4 people, 33.33%

What are other side effects people have besides Rickets? *

Oedema Peripheral (superficial swelling): 10 people, 83.33%
Dyspnea (difficult or laboured breathing): 7 people, 58.33%
Fatigue (feeling of tiredness): 7 people, 58.33%
High Blood Pressure: 6 people, 50.00%
Acute Kidney Failure: 6 people, 50.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 50.00%
Night Sweats (sweating in night): 6 people, 50.00%
Rashes (redness): 5 people, 41.67%
Blood Creatinine Increased: 5 people, 41.67%
Chest Pain: 5 people, 41.67%

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 41.67%
Vena Cava Thrombosis (clotting of the blood in large vein carrying deoxygenated blood into the heart): 4 people, 33.33%
Infection: 4 people, 33.33%
Arterial Disorder: 4 people, 33.33%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 33.33%
Depression: 4 people, 33.33%
Device Related Infection: 4 people, 33.33%
Dyslipidaemia (abnormal amount of lipids): 4 people, 33.33%
Fever: 4 people, 33.33%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Febuxostat and have Rickets?

- Check whether Rickets is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Febuxostat:

Febuxostat (9,693 reports)

Rickets treatments and more:

Rickets (30,776 reports)

Browse all side effects of Febuxostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rickets:

Rickets (1,086 drugs)

Browse all the conditions that are associated with Rickets:

Rickets (1,459 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on febuxostat (the active ingredients of Febuxostat) and Febuxostat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.