Fentanyl citrate and Hypertonia - a phase IV clinical study of FDA data

Summary:

Hypertonia is reported as a side effect among people who take Fentanyl citrate (fentanyl citrate), especially for people who are female, 40-49 old, also take Lorazepam, and have Sedation.

The phase IV clinical study analyzes which people have Hypertonia when taking Fentanyl citrate. It is created by eHealthMe based on reports of 21,231 people who have side effects when taking Fentanyl citrate from the FDA, and is updated regularly.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

What is Hypertonia?

Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch) is found to be associated with 491 drugs and 692 conditions by eHealthMe. Check the latest studies of Hypertonia.

On Jul, 14, 2026

21,231 people reported to have side effects when taking Fentanyl citrate.
Among them, 14 people (0.07%) have Hypertonia.

Could Fentanyl citrate cause Hypertonia?

Among these 14 people:

What is the gender of people who have Hypertonia when taking Fentanyl citrate? *

female: 76.92 %
male: 23.08 %

What is the age of people who have Hypertonia when taking Fentanyl citrate? *

What are other drugs people take besides Fentanyl citrate? *

Zinacef: 1 person, 7.14%
Midazolam: 1 person, 7.14%
Amoxicillin: 1 person, 7.14%
Aspirin: 1 person, 7.14%
Cefazolin: 1 person, 7.14%
Cellcept: 1 person, 7.14%
Fentanyl Transdermal System: 1 person, 7.14%
Garamycin: 1 person, 7.14%
Lopressor: 1 person, 7.14%
Lorazepam: 1 person, 7.14%

What are other side effects people have besides Hypertonia? *

Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 5 people, 35.71%
Agitation (state of anxiety or nervous excitement): 4 people, 28.57%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 4 people, 28.57%
Hyperreflexia (overactive or over responsive reflexes): 3 people, 21.43%
Bacteraemia (presence of bacteria in the blood): 3 people, 21.43%
Clonus (series of involuntary, rhythmic, muscular contractions and relaxations): 3 people, 21.43%
Confusional State: 3 people, 21.43%
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 3 people, 21.43%
Aggression: 2 people, 14.29%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 14.29%

What are the existing conditions these people have? *

Sedation: 3 people, 21.43%
Breast Cancer: 2 people, 14.29%
Urinary Tract Infection: 1 person, 7.14%
Neck Pain: 1 person, 7.14%
General Anaesthesia: 1 person, 7.14%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 1 person, 7.14%
Bipolar Disorder (mood disorder): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl citrate and have Hypertonia?

- Check whether Hypertonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fentanyl citrate:

Fentanyl citrate (21,294 reports)

Hypertonia treatments and more:

Hypertonia (11,073 reports)

Browse all side effects of Fentanyl citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertonia:

Hypertonia (491 drugs)

Browse all the conditions that are associated with Hypertonia:

Hypertonia (692 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Fentanyl citrate) and Fentanyl citrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.