Fioricet and Night sweats - a phase IV clinical study of FDA data

Summary:

Night sweats is reported as a side effect among people who take Fioricet (acetaminophen; butalbital; caffeine), especially for people who are female, 40-49 old, also take Flexeril, and have Pain.

The phase IV clinical study analyzes which people have Night sweats when taking Fioricet. It is created by eHealthMe based on reports of 11,479 people who have side effects when taking Fioricet from the FDA, and is updated regularly.

What is Fioricet?

Fioricet has active ingredients of acetaminophen; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 12,423 Fioricet users. Check the latest studies of Fioricet.

What is Night sweats?

Night sweats (sweating in night) is found to be associated with 1,529 drugs and 1,689 conditions by eHealthMe. Check the latest studies of Night sweats.

On Jul, 28, 2026

11,479 people reported to have side effects when taking Fioricet.
Among them, 57 people (0.5%) have Night sweats.

Among these 57 people:

What is the gender of people who have Night sweats when taking Fioricet? *

female: 89.09 %
male: 10.91 %

What is the age of people who have Night sweats when taking Fioricet? *

What are other drugs people take besides Fioricet? *

What are other side effects people have besides Night sweats? *

Nausea (feeling of having an urge to vomit): 24 people, 42.11%
Back Pain: 23 people, 40.35%
Fatigue (feeling of tiredness): 21 people, 36.84%
Insomnia (sleeplessness): 21 people, 36.84%
Chest Pain: 19 people, 33.33%
Stress And Anxiety: 17 people, 29.82%
Joint Pain: 17 people, 29.82%
Pain: 17 people, 29.82%
Dyspnea (difficult or laboured breathing): 15 people, 26.32%
Weight Decreased: 14 people, 24.56%

What are the existing conditions these people have? *

Pain: 15 people, 26.32%
High Blood Cholesterol: 8 people, 14.04%
Arthropod Sting (arthropod bite): 7 people, 12.28%
Dyspnea (difficult or laboured breathing): 7 people, 12.28%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 12.28%
Osteopenia (a condition where bone mineral density is lower than normal): 7 people, 12.28%
Breast Cancer: 6 people, 10.53%
Primary Immunodeficiency Syndrome: 5 people, 8.77%
Immunodeficiency Common Variable: 5 people, 8.77%
Osteoporosis (bones weak and more likely to break): 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

Do you take Fioricet and have Night sweats?

- Check whether Night sweats is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fioricet:

Fioricet (12,423 reports)

Night sweats treatments and more:

Night sweats (40,332 reports)

How severe was Night sweats and when was it recovered:

Night sweats in Fioricet

Expand to all the drugs that have ingredients of acetaminophen; butalbital; caffeine:

Night sweats and drugs with ingredients of acetaminophen; butalbital; caffeine (395 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fioricet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Night sweats:

Night sweats (1,529 drugs)

Browse all the conditions that are associated with Night sweats:

Night sweats (1,689 conditions)

Related publications that referenced our studies

Murday HK, Rusli FD, Blandy C, Vollenhoven B, "Night sweats: it may be hemochromatosis", Climacteric, 2016 Jul .
Murday HK, Rusli FD, Blandy C, Vollenhoven B, "Night sweats: it may be hemochromatosis", Climacteric, 2016 Jul .

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; butalbital; caffeine (the active ingredients of Fioricet) and Fioricet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.